TMPRSS4 and NLRX1

Data Source:
BioGRID (biochemical)

		TMPRSS4	NLRX1
Description		transmembrane serine protease 4	NLR family member X1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Membrane Secretory Granule	Mitochondrion Mitochondrial Outer Membrane Plasma Membrane Cell Junction
	Molecular Function	Serine-type Endopeptidase Activity Scavenger Receptor Activity Protein Binding Serine-type Peptidase Activity	Protein Binding ATP Binding
	Biological Process	Proteolysis Endocytosis Response To Wounding Regulation Of Gene Expression Protein Processing Negative Regulation Of Growth Rate Positive Regulation Of Viral Entry Into Host Cell	Viral Process Negative Regulation Of Type I Interferon Production Negative Regulation Of Interferon-beta Production Negative Regulation Of Interleukin-6 Production Intracellular Signal Transduction Negative Regulation Of RIG-I Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Negative Regulation Of Innate Immune Response Negative Regulation Of Inflammatory Response
Pathways			DDX58/IFIH1-mediated induction of interferon-alpha/beta Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS			Mean reticulocyte volume ( 32888494)
Interacting Genes		14 interacting genes: BNIP3L CLEC7A CLRN1 ERVFRD-1 FAM209A FNDC9 GPX8 KASH5 LMNA RASGRP4 SIGLEC12 SUSD3 SYNE4 TMEM79	1 interacting genes: SARM1
Entrez ID		56649	79671
HPRD ID		05952	17640
Ensembl ID		ENSG00000137648	ENSG00000160703
Uniprot IDs		B7Z458 B7Z8X1 B7Z900 Q9NRS4	Q86UT6
PDB IDs			3UN9
Enriched GO Terms of Interacting Partners?
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