MEPCE and ALKBH4

Data Source:
BioGRID (genetic interference)

		MEPCE	ALKBH4
Description		methylphosphate capping enzyme	alkB homolog 4, lysine demethylase
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus 7SK SnRNP Ribonucleoprotein Complex	Nucleolus Cytoplasm Midbody Contractile Ring
	Molecular Function	RNA Binding Protein Binding O-methyltransferase Activity RNA Methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity SnRNA Binding 7SK SnRNA Binding RNA 5'-methyltransferase Activity	Actin Binding Protein Binding Oxidoreductase Activity 2-oxoglutarate-dependent Dioxygenase Activity Demethylase Activity Oxidative DNA Demethylase Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II RNA Methylation SnRNA Metabolic Process Negative Regulation Of Chromatin Binding SnRNA Modification Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of SnRNA Transcription By RNA Polymerase II	Chromatin Organization Protein Demethylation Actomyosin Structure Organization Oxidative DNA Demethylation Cleavage Furrow Ingression Oxidative Demethylation DNA Demethylation Regulation Of Chromatin Organization
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Morning person ( 30696823)
Interacting Genes		2 interacting genes: ERBB2 RN7SK	18 interacting genes: BPIFA1 DTX2 EIF3C EP300 FAM168A GORASP2 HSF4 LCN2 MLLT1 MLLT3 MTMR6 NIF3L1 PSMA6 TCF4 TES TRAF4 TXNL4B ZFHX3
Entrez ID		56257	54784
HPRD ID		07889	07875
Ensembl ID		ENSG00000146834	ENSG00000160993
Uniprot IDs		Q7L2J0	Q9NXW9
PDB IDs		5UNA 6DCB 6DCC
Enriched GO Terms of Interacting Partners?
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