ALKBH4 and LCN2

Data Source:
BioGRID (two hybrid)

		ALKBH4	LCN2
Description		alkB homolog 4, lysine demethylase	lipocalin 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Midbody Contractile Ring	Extracellular Region Extracellular Space Specific Granule Lumen Extracellular Exosome
	Molecular Function	Actin Binding Protein Binding Oxidoreductase Activity 2-oxoglutarate-dependent Dioxygenase Activity Demethylase Activity Oxidative DNA Demethylase Activity Metal Ion Binding	Iron Ion Binding Protein Binding Small Molecule Binding Identical Protein Binding Enterobactin Binding
	Biological Process	Chromatin Organization Protein Demethylation Actomyosin Structure Organization Oxidative DNA Demethylation Cleavage Furrow Ingression Oxidative Demethylation DNA Demethylation Regulation Of Chromatin Organization	Cellular Iron Ion Homeostasis Apoptotic Process Siderophore Transport Cytokine-mediated Signaling Pathway Antimicrobial Humoral Response Defense Response To Bacterium Neutrophil Degranulation Innate Immune Response Sequestering Of Iron Ion Positive Regulation Of Cold-induced Thermogenesis
Pathways			Interleukin-4 and Interleukin-13 signaling Neutrophil degranulation Metal sequestration by antimicrobial proteins Iron uptake and transport Iron uptake and transport
Drugs			Methyl nonanoate 2,3-Dihydroxy-Benzoic Acid Carboxymycobactin S 2,3,-Dihydroxybenzoylserine Carboxymycobactin T Trencam-3,2-Hopo
Diseases
GWAS		Morning person ( 30696823)
Interacting Genes		18 interacting genes: BPIFA1 DTX2 EIF3C EP300 FAM168A GORASP2 HSF4 LCN2 MLLT1 MLLT3 MTMR6 NIF3L1 PSMA6 TCF4 TES TRAF4 TXNL4B ZFHX3	61 interacting genes: ALDH7A1 ALKBH4 ASB10 ASPH BEX2 BMF C20orf85 CAMLG CCNC CDSN CHIC2 CLMP CTDSP2 EHHADH FAAP20 FAM25A FAM25C FAM25G HDDC2 HGF LAIR2 LNPEP LRP2 LY96 MAGED4B MMP2 MMP9 MSRB3 MYDGF NDUFB2 NEIL2 ODAPH P4HB PDIA4 PELI1 PICK1 PIN1 POLL POU4F2 PRKAA2 PTRH1 RAMP2 SCNM1 SEC61G SGTA SGTB TBC1D21 TRAPPC2L TRH TRIAP1 TRIM32 TSG101 TTC23 TXN2 UBASH3A UBE2F UBQLN1 UBQLN2 VEZF1 XRN2 ZBED1
Entrez ID		54784	3934
HPRD ID		07875	02551
Ensembl ID		ENSG00000160993	ENSG00000148346
Uniprot IDs		Q9NXW9	P80188
PDB IDs			1DFV 1L6M 1NGL 1QQS 1X71 1X89 1X8U 3BY0 3CBC 3CMP 3DSZ 3DTQ 3FW4 3FW5 3HWD 3HWE 3HWF 3HWG 3I0A 3K3L 3PEC 3PED 3T1D 3TF6 3TZS 3U0D 4GH7 4IAW 4IAX 4K19 4MVI 4MVK 4MVL 4QAE 4ZFX 4ZHC 4ZHD 4ZHF 4ZHG 4ZHH 5JR8 5KHP 5KIC 5KID 5MHH 5N47 5N48 5NKN 6GQZ 6GR0 6O5D 6QMU 6S8V 6SUA
Enriched GO Terms of Interacting Partners?
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