KIAA1217 and KRT27

Data Source:
BioGRID (two hybrid)

		KIAA1217	KRT27
Description		KIAA1217	keratin 27
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Molecular_function Enzyme Regulator Activity	Molecular_function Structural Molecule Activity Protein Binding
	Biological Process	Embryonic Skeletal System Development Regulation Of Catalytic Activity	Biological_process Hair Follicle Morphogenesis Keratinization Cornification
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Breast cancer and/or colorectal cancer ( 29698419) Cognitive performance ( 20125193) Coronary artery disease ( 29212778) Diverticular disease ( 30177863) Lobe attachment (rater scored) ( 29198719) Lobe attachment (rater-scored or self-reported) ( 29198719) Moderate-to-late spontaneous preterm birth ( 31194736) Obesity (early onset extreme) ( 23563609) Schizophrenia ( 30285260) Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770) Triglyceride levels x loop diuretics use interaction ( 31806883)	Asthma ( 31959851)
Interacting Genes		23 interacting genes: ABI1 ABI2 ALKBH7 EXOC8 EXOSC5 FHL2 FXR2 GCC1 GOLGA2 HSBP1 INCA1 KRT15 KRT27 KRT31 NCK2 PTK6 RINT1 SIAH1 SORBS3 TEX11 TRAF1 TRAF2 VPS52	145 interacting genes: AARD ABI2 AMOT ARFIP1 ARHGEF6 ATP6V1D BCAS2 BEX2 BFSP1 BFSP2 C19orf44 C1orf216 C21orf58 CCBE1 CCDC138 CCDC146 CCDC185 CCDC187 CCDC22 CCDC68 CCHCR1 CCNC CEP95 CFAP58 COX5B DPPA3 DTNB DUSP26 EXOC3L1 EXOSC5 FAM107A FAM110A FMNL2 GADD45GIP1 GAS8 GFAP GNG13 GOLGA1 GPS2 GSTK1 HAPLN2 HDAC4 HGS HOOK3 HOXB9 HSPBP1 ICA1L IGF1R INSR INSRR JOSD1 KANK2 KIAA1217 KLHL38 KRT1 KRT2 KRT20 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT7 KRT71 KRT72 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT81 KRT82 KRT83 KRT85 KRT86 LKAAEAR1 LMNTD2 MATR3 MBD3L2 MID2 MORN4 MOS MTMR9 NDC80 NDUFAF3 NTAQ1 NUP54 NUP58 ODAD3 OIP5 PBX3 PCDHB14 PNN POLL PPP1R18 PRPH PSMC5 RASAL3 RBM41 RCOR3 RNF39 RTP5 RUNX1T1 SCNM1 SDHAF1 SEMA4C SGF29 SLC22A5 SLIRP SMARCC2 SMARCD1 SMARCE1 SNAPIN SSC5D SSX3 SUFU SUOX TBRG4 TEAD4 TEDC2 TEX28 THAP7 TNNT1 TRAF3IP3 TRIML2 TSKS TTC23 TXLNA TXLNB TXN2 USHBP1 USP2 VPS37C WASHC3 XRCC4 ZC3H14 ZFYVE26 ZNF3 ZNF580 ZNF581 ZNF669 ZNF80
Entrez ID		56243	342574
HPRD ID		11132	17244
Ensembl ID		ENSG00000120549	ENSG00000171446
Uniprot IDs		B7ZM29 Q5T5P2	Q7Z3Y8
PDB IDs
Enriched GO Terms of Interacting Partners?
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