SMG9 and PPP2R3C

Data Source:
BioGRID (two hybrid)

		SMG9	PPP2R3C
Description		SMG9 nonsense mediated mRNA decay factor	protein phosphatase 2 regulatory subunit B''gamma
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleoplasm Golgi Apparatus Centrosome Spindle Cytosol
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Eye Development In Utero Embryonic Development Brain Development Heart Development	Microtubule Cytoskeleton Organization B Cell Homeostasis Regulation Of Antimicrobial Humoral Response Cortical Cytoskeleton Organization Activation Of Protein Kinase Activity Regulation Of Dephosphorylation T Cell Homeostasis Positive Regulation Of B Cell Differentiation Spleen Development Regulation Of Mitochondrial Depolarization
Pathways		Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Lymphocyte counts ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 29403010) Monocyte count ( 32888494)	Atopic dermatitis ( 26482879) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Colorectal carcinoma in primary sclerosing cholangitis ( 28779025) Lymphocyte counts ( 32888494 27863252) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		39 interacting genes: AGTRAP AK8 ARFIP2 CCDC57 CEP76 CMTM4 CTAG1A CTAG1B DGAT2L6 FNTB GOLGA2 GSG1 HSF2BP INCA1 KRT31 KRT34 KRTAP10-8 MTUS2 NFKBID PFDN5 PHF1 PLEKHG4 PNMA3 PPP2R3C PRKAR1B RASSF10 REL SLC17A9 SLC50A1 SYP TCF4 TRAF2 TRIM23 TRIM27 TRIP6 TSC1 TTC19 ZMYND12 ZNF655	15 interacting genes: CCDC146 CCDC33 CMTM5 ENKD1 FAM161A FAM161B HSPB1 IKBKB MOAP1 MTNR1A POLR1C PRPF31 RTN3 SMG9 TRIM14
Entrez ID		56006	55012
HPRD ID		07800	12622
Ensembl ID		ENSG00000105771	ENSG00000092020
Uniprot IDs		A0A024R0Q0 Q9H0W8	Q969Q6
PDB IDs		6L54 6SYT 6Z3R
Enriched GO Terms of Interacting Partners?
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