CFC1 and ELF4

Data Source:
BioGRID (biochemical)

		CFC1	ELF4
Description		cripto, FRL-1, cryptic family 1	E74 like ETS transcription factor 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Extracellular Region Plasma Membrane Cell Surface Anchored Component Of Membrane	Chromatin Nucleus Nucleoplasm Nuclear Body PML Body
	Molecular Function	Molecular_function Signaling Receptor Binding Nodal Binding Activin Receptor Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Blood Vessel Development Determination Of Left/right Symmetry Gastrulation Heart Development Anterior/posterior Pattern Specification Nodal Signaling Pathway Anatomical Structure Development	Natural Killer Cell Proliferation NK T Cell Proliferation Regulation Of Transcription By RNA Polymerase II Cell Differentiation Innate Immune Response Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Signaling by NODAL Regulation of signaling by NODAL
Drugs
Diseases		Conotruncal heart malformations, including: Double-outlet right ventricle; Persistent truncus arteriosus; Conotruncal anomaly face syndrome Heterotaxy; Situs ambiguus
GWAS			Bipolar disorder ( 31043756)
Interacting Genes			9 interacting genes: CASP4 FBXO4 FBXO7 NPM1 PML RUNX1 SET SKP2 UBB
Entrez ID		55997	2000
HPRD ID		05548	06499
Ensembl ID		ENSG00000136698	ENSG00000102034
Uniprot IDs		A0A087WWV2 A0A087WX98 P0CG37	Q99607
PDB IDs
Enriched GO Terms of Interacting Partners?
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