APOM and KLF6

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		APOM	KLF6
Description		apolipoprotein M	Kruppel like factor 6
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Very-low-density Lipoprotein Particle Low-density Lipoprotein Particle High-density Lipoprotein Particle Discoidal High-density Lipoprotein Particle Spherical High-density Lipoprotein Particle	Chromatin Fibrillar Center Nucleus Nucleoplasm Nucleolus Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Lipid Transporter Activity Phospholipid Binding Antioxidant Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Retinoid Metabolic Process Response To Glucose Cholesterol Efflux High-density Lipoprotein Particle Remodeling High-density Lipoprotein Particle Assembly High-density Lipoprotein Particle Clearance Negative Regulation Of Plasma Lipoprotein Oxidation Lipoprotein Metabolic Process Cholesterol Homeostasis Reverse Cholesterol Transport Cellular Oxidant Detoxification	Regulation Of Transcription By RNA Polymerase II B Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Retinoid metabolism and transport
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576 29875488) Inflammatory bowel disease ( 28067908) Lung adenocarcinoma ( 19836008) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Malaria ( 31844061) Rheumatoid arthritis ( 21844665) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Squamous cell lung carcinoma ( 28604730) Ulcerative colitis ( 28067908)	Asthma (bronchodilator response) ( 23508266) Coronary artery calcification ( 23870195) Diastolic blood pressure ( 27841878) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Heel bone mineral density ( 30598549 28869591) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Plasma anti-thyroglobulin levels ( 29678681) Red blood cell count ( 32888494)
Interacting Genes		2 interacting genes: HGH1 KLF6	16 interacting genes: APOM APP CELSR2 EHMT2 FBL GTF3C1 HDAC3 KLF4 LCOR NOP56 NUFIP1 PNO1 POLA2 SP1 TAF9 TP53
Entrez ID		55937	1316
HPRD ID		06068	03632
Ensembl ID		ENSG00000204444	ENSG00000067082
Uniprot IDs		A0A1U9X793 O95445	D3GC14 Q99612
PDB IDs		2WEW 2WEX 2YG2
Enriched GO Terms of Interacting Partners?
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