KIZ and SPEF1

Data Source:
BioGRID (genetic interference)

		KIZ	SPEF1
Description		kizuna centrosomal protein	sperm flagellar 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cell Projection	Cytoplasm Microtubule Microvillus Axoneme Basolateral Plasma Membrane Apical Plasma Membrane Lamellipodium Filopodium Ciliary Tip 9+2 Motile Cilium Axonemal Central Apparatus
	Molecular Function	Protein Binding Protein Kinase Binding	Molecular_function Actin Binding Protein Binding Microtubule Binding
	Biological Process	Spindle Organization	Microtubule Bundle Formation Cilium Movement Negative Regulation Of Microtubule Depolymerization Cell Migration Lamellipodium Assembly Filopodium Assembly Regulation Of Cytoskeleton Organization Negative Regulation Of Cell Death Axonemal Central Apparatus Assembly Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Pathways
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder ( 30804558) Height ( 31562340)	Cognitive decline rate in late mild cognitive impairment ( 26252872) Hippocampal volume ( 29860282) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		3 interacting genes: MEOX2 TACC3 TFIP11	5 interacting genes: CYSRT1 KRT40 KRTAP13-2 PLEKHF2 ZBED1
Entrez ID		55857	25876
HPRD ID		12760	09839
Ensembl ID		ENSG00000088970	ENSG00000101222
Uniprot IDs		A0A087X251 Q2M2Z5	Q9Y4P9
PDB IDs			2EE7
Enriched GO Terms of Interacting Partners?
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