ARHGAP15 and CD93

Data Source:
HPRD (two hybrid)

		ARHGAP15	CD93
Description		Rho GTPase activating protein 15	CD93 molecule
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane	Plasma Membrane Cell Surface Integral Component Of Membrane Secretory Granule Membrane Specific Granule Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	GTPase Activator Activity	Complement Component C1q Complex Binding Calcium Ion Binding Protein Binding Carbohydrate Binding Signaling Receptor Activity
	Biological Process	Signal Transduction Regulation Of Cell Shape Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Phagocytosis Viral Process Macrophage Activation Neutrophil Degranulation Cell-cell Adhesion
Pathways		Rho GTPase cycle	Neutrophil degranulation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Alcohol consumption ( 31358974) Alcohol consumption (drinks per week) ( 30643258 30679032) Allergic disease (asthma, hay fever or eczema) ( 29083406) Bitter alcoholic beverage consumption ( 31046077) Chin dimples ( 27182965) Chronotype ( 30696823) Coronary artery disease ( 29212778 33020668) Diastolic blood pressure ( 30224653) Diisocyanate-induced asthma ( 25918132) Diverticular disease ( 30177863 28585551 30661054) Diverticulitis ( 28585551) Electrodermal activity ( 25387706) Eosinophil counts ( 32888494) Experiencing mood swings ( 29500382) Extremely high intelligence ( 29520040) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Heel bone mineral density ( 30598549) Hematocrit ( 32888494) Hemoglobin ( 32888494) Household income (MTAG) ( 31844048) Intelligence ( 28530673) Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494) Mean platelet volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Metabolite levels ( 23823483) Monocyte count ( 32888494) Mood instability ( 31168069) Morning person ( 30696823) Neutrophil percentage of white cells ( 32888494) Platelet distribution width ( 32888494) Quantitative traits ( 19197348) Response to SSRI (symptom remission) ( 29160301) Smooth-surface caries ( 24556642) Systemic lupus erythematosus ( 33536424) Toenail selenium levels ( 25343990) Tooth agenesis ( 29364747) Vascular brain injury ( 25188341) White blood cell count ( 32888494 27863252)	Liver enzyme levels (alanine transaminase) ( 24124411) Obesity-related traits ( 23251661) Venous thromboembolism ( 26888256 31676865)
Interacting Genes		8 interacting genes: APP CD93 KDM1A PRNP RAC1 SMURF1 SNCA TGFBR1	23 interacting genes: ARHGAP15 BAG6 C1QA COL1A1 COL1A2 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COPS5 F12 GIPC1 KIR2DL2 KNG1 MBL2 MSN MYD88 RANBP1 SCYL1 TENT5A UBQLN2
Entrez ID		55843	22918
HPRD ID		06447	00396
Ensembl ID		ENSG00000075884	ENSG00000125810
Uniprot IDs		Q53QZ3	Q9NPY3
PDB IDs		3BYI
Enriched GO Terms of Interacting Partners?
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