ST6GALNAC1 and NDST1

Data Source:
HPRD (in vitro, in vivo)

		ST6GALNAC1	NDST1
Description		ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1	N-deacetylase and N-sulfotransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Integral Component Of Membrane	Golgi Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Alpha-N-acetylgalactosaminide Alpha-2,6-sialyltransferase Activity Sialyltransferase Activity	Protein Binding [heparan Sulfate]-glucosamine N-sulfotransferase Activity Deacetylase Activity Heparan Sulfate N-deacetylase Activity
	Biological Process	Protein Glycosylation Oligosaccharide Biosynthetic Process Sialylation	Cardiac Septum Development Glycosaminoglycan Biosynthetic Process Protein Sulfation Inflammatory Response Respiratory Gaseous Exchange By Respiratory System Cell Population Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Heparan Sulfate Proteoglycan Biosynthetic Process, Polysaccharide Chain Biosynthetic Process Heparin Biosynthetic Process Forebrain Development Midbrain Development Aorta Development Positive Regulation Of MAPK Cascade Positive Regulation Of Smoothened Signaling Pathway Embryonic Neurocranium Morphogenesis Embryonic Viscerocranium Morphogenesis Coronary Vasculature Development
Pathways		Sialic acid metabolism	HS-GAG biosynthesis
Drugs			Adenosine 3',5'-diphosphate
Diseases
GWAS			Blood protein levels ( 30072576) Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Neutrophil count ( 32888494)
Interacting Genes		1 interacting genes: EXOSC2
Entrez ID		55808	3340
HPRD ID		15340	02912
Ensembl ID		ENSG00000070526	ENSG00000070614
Uniprot IDs		Q9NSC7	A8K8T3 B7Z1Q0 E7EVJ3 P52848
PDB IDs			1NST
Enriched GO Terms of Interacting Partners?
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