TBC1D23 and TOMM70

Data Source:
BioGRID (proximity labelling technology)

		TBC1D23	TOMM70
Description		TBC1 domain family member 23	translocase of outer mitochondrial membrane 70
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GO Annotations	Cellular Component	Golgi Apparatus Trans-Golgi Network Cytosol Cytoplasmic Vesicle WASH Complex	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Protein Transmembrane Transporter Activity Mitochondrion Targeting Sequence Binding
	Biological Process	Brain Development Vesicle-mediated Transport Neuron Projection Development Retrograde Transport, Endosome To Golgi Vesicle Tethering To Golgi Embryonic Brain Development	Activation Of Innate Immune Response Positive Regulation Of Defense Response To Virus By Host Protein Targeting To Mitochondrion Macroautophagy Protein Import Into Mitochondrial Matrix Positive Regulation Of Interferon-beta Production Regulation Of Apoptotic Process Protein Insertion Into Mitochondrial Inner Membrane Cellular Response To Virus
Pathways			Mitochondrial protein import PINK1-PRKN Mediated Mitophagy Ub-specific processing proteases
Drugs
Diseases
GWAS		Axial length ( 24144296) Refractive error ( 32231278) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		12 interacting genes: CAGE1 EHD2 EIF3B FAM214B KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP4-12 NOPCHAP1 SSBP3 STK11 WDR62	7 interacting genes: HSP90AA1 HSPA1A HSPA1B HSPB1 IRF3 PRKN SNAPIN
Entrez ID		55773	9868
HPRD ID		07727	16194
Ensembl ID		ENSG00000036054	ENSG00000154174
Uniprot IDs		Q9NUY8	O94826
PDB IDs		6JL7 6JM5	7KDT
Enriched GO Terms of Interacting Partners?
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