IFT122 and ZNF148

Data Source:
BioGRID (two hybrid)

		IFT122	ZNF148
Description		intraflagellar transport 122	zinc finger protein 148
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cilium Membrane Intraciliary Transport Particle A Photoreceptor Connecting Cilium Ciliary Basal Body Ciliary Tip Non-motile Cilium	Nucleoplasm Golgi Apparatus
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Neural Tube Closure Embryonic Body Morphogenesis Embryonic Heart Tube Development Intraciliary Retrograde Transport Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Negative Regulation Of Smoothened Signaling Pathway Camera-type Eye Morphogenesis Limb Development Cilium Assembly Protein Localization To Cilium Non-motile Cilium Assembly	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cellular Defense Response Gamete Generation Negative Regulation Of Gene Expression Substantia Nigra Development Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Assembly
Pathways		Hedgehog 'off' state Intraflagellar transport
Drugs
Diseases		Cranioectodermal dysplasia
GWAS		Diisocyanate-induced asthma ( 25918132) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Urate levels ( 31578528)
Interacting Genes			25 interacting genes: CAVIN1 CEP63 CEP70 CLK1 DEUP1 EP300 GLRX3 GORASP2 JADE1 KRT31 KRT34 LNX1 LNX2 NUTM2F PFDN5 PLEKHG4 PNMA1 POU6F2 SIAH1 STAT3 TP53 TRIM10 UBC USP54 ZMYND12
Entrez ID		55764	7707
HPRD ID		06922	03540
Ensembl ID		ENSG00000163913	ENSG00000163848
Uniprot IDs		B3KUD1 B4DST2 Q9HBG6	Q9UQR1
PDB IDs
Enriched GO Terms of Interacting Partners?
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