PACS1 and GDI1

Data Source:
BioGRID (affinity chromatography technology)

		PACS1	GDI1
Description		phosphofurin acidic cluster sorting protein 1	GDP dissociation inhibitor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Cytosol COPI-coated Vesicle	Cytoplasm Golgi Apparatus Cytosol Axon Midbody Protein-containing Complex Neuronal Cell Body Myelin Sheath
	Molecular Function	Protein Binding Ion Channel Binding	GDP-dissociation Inhibitor Activity Rab GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding
	Biological Process	Protein Localization To Golgi Apparatus Regulation Of Defense Response To Virus By Virus Protein Localization To Plasma Membrane	Signal Transduction Protein Transport Vesicle-mediated Transport Rab Protein Signal Transduction Positive Regulation Of GTPase Activity Positive Regulation Of Axon Extension Negative Regulation Of Axonogenesis Regulation Of Small GTPase Mediated Signal Transduction Response To Calcium Ion Negative Regulation Of Protein Targeting To Membrane
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression	RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases			Non-syndromic X-linked mental retardation
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 21926972 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Electroencephalogram traits ( 25387704) Immature fraction of reticulocytes ( 32888494) Obesity (early onset extreme) ( 23563609) Serum uric acid levels ( 32514006)
Interacting Genes		10 interacting genes: CLCN7 CSNK2A1 FURIN GGA3 IGF2R JUN PKD2 PPP2CA PPP2CB VAMP4	15 interacting genes: CDC42 EPB41 GNL1 LNX1 PSEN1 RAB1B RAB27A RAB3B RAB6A RAB9A RABAC1 RAC2 RHOH TK1 UBQLN4
Entrez ID		55690	2664
HPRD ID		06320	02114
Ensembl ID		ENSG00000175115	ENSG00000203879
Uniprot IDs		A0A024R5H6 Q6VY07	A0A0S2Z3X8 P31150
PDB IDs
Enriched GO Terms of Interacting Partners?
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