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HIF1AN and ANKRD37
Data Source:
BioGRID
(two hybrid)
HIF1AN
ANKRD37
Description
hypoxia inducible factor 1 subunit alpha inhibitor
ankyrin repeat domain 37
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Perinuclear Region Of Cytoplasm
Nucleoplasm
Mitochondrion
Cytosol
Molecular Function
Notch Binding
Protein Binding
Ferrous Iron Binding
Zinc Ion Binding
2-oxoglutarate-dependent Dioxygenase Activity
Oxygen Sensor Activity
Carboxylic Acid Binding
Peptidyl-histidine Dioxygenase Activity
Peptidyl-asparagine 3-dioxygenase Activity
Protein Homodimerization Activity
NF-kappaB Binding
Ankyrin Repeat Binding
Hypoxia-inducible Factor-asparagine Oxygenase Activity
Protein Binding
Biological Process
Protein Phosphopantetheinylation
Peptidyl-histidine Hydroxylation
Peptidyl-aspartic Acid Hydroxylation
Peptidyl-asparagine Hydroxylation
Positive Regulation Of Myoblast Differentiation
Negative Regulation Of Notch Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Positive Regulation Of Vasculogenesis
Pathways
Cellular response to hypoxia
Drugs
D-tartaric acid
N-(carboxycarbonyl)-D-phenylalanine
Diseases
GWAS
Body mass index (
28892062
25673413
)
Brain morphology (MOSTest) (
32665545
)
Cerebrospinal fluid t-tau:AB1-42 ratio (
30153862
)
Metabolite levels (
23823483
)
Palmitoleic acid (16:1n-7) levels (
28298293
23362303
)
Interacting Genes
19 interacting genes:
ANKK1
ANKRD12
ANKRD37
ANKRD50
ASB13
ASB4
ASB7
ASB9
FBF1
HDAC1
HDAC2
HDAC3
HIF1A
INVS
NAA10
SIAH1
TP53BP2
UACA
VHL
2 interacting genes:
HIF1AN
ZNF76
Entrez ID
55662
353322
HPRD ID
09426
17461
Ensembl ID
ENSG00000166135
ENSG00000186352
Uniprot IDs
Q9NWT6
B4E066
Q7Z713
PDB IDs
1H2K
1H2L
1H2M
1H2N
1IZ3
1MZE
1MZF
1YCI
2CGN
2CGO
2ILM
2W0X
2WA3
2WA4
2XUM
2Y0I
2YC0
2YDE
3D8C
3KCX
3KCY
3OD4
3P3N
3P3P
4AI8
4B7E
4B7K
4BIO
4JAA
4NR1
4Z1V
4Z2W
5JWK
5JWL
5JWP
5OP6
5OP8
5OPC
6H9J
6HA6
6HC8
6HKP
6HL5
6HL6
6RUJ
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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