ANKRD10 and SHC3

Data Source:
BioGRID (two hybrid)

		ANKRD10	SHC3
Description		ankyrin repeat domain 10	SHC adaptor protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cellular_component Cytosol Plasma Membrane
	Molecular Function	Protein Binding	Phosphotyrosine Residue Binding Protein Binding Protein Kinase Binding Receptor Tyrosine Kinase Binding
	Biological Process		MAPK Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Ras Protein Signal Transduction Axon Guidance Central Nervous System Development
Pathways			Signalling to RAS Signalling to RAS RAF/MAP kinase cascade RET signaling
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Refractive error ( 32231278)	Logical memory (delayed recall) in Alzheimer's disease dementia ( 29274321) Pelvic organ prolapse (moderate/severe) ( 26545240) Response to statins (LDL cholesterol change) ( 22331829) Superior parietal cortex volume ( 31530798) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		16 interacting genes: APPBP2 ATG9A CSTF2 FAM222B FOXI1 GIGYF1 OTX1 PEF1 PITX1 POGZ POU6F2 SHC3 SNRPC TLX3 TRIP13 ZIC1	58 interacting genes: ALK ANKRD10 APP AR ARHGAP32 ASPG AXL BMF CCNC CDCA4 CEACAM6 COPS6 CT55 DOK3 EGFR ERBB2 ERBB3 ERBB4 FLT4 FTO GAB1 GOLGA2 GOLGA6L9 GRB2 KIT KRT31 KRT33B KRT34 KRT35 KRT39 KRT40 KRT86 MET NTRK1 NTRK2 PMF1 PNMA1 PPP1R16B PRKAR1B PSMD8 REL RET SH3GL3 SMYD3 STX11 TRAF1 TRAF2 TRIM35 TRIM54 TSC1 UBAP2 USHBP1 USP54 VPS28 WWOX YPEL3 YPEL5 ZMYND12
Entrez ID		55608	53358
HPRD ID		12455	12005
Ensembl ID		ENSG00000088448	ENSG00000148082
Uniprot IDs		A0A024RE01 Q9NXR5	Q92529
PDB IDs
Enriched GO Terms of Interacting Partners?
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