CNOT11 and MEOX1

Data Source:
BioGRID (two hybrid)

		CNOT11	MEOX1
Description		CCR4-NOT transcription complex subunit 11	mesenchyme homeobox 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol CCR4-NOT Complex	Chromatin Nucleus Cytoplasm
	Molecular Function	Molecular_function Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding HMG Box Domain Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening Regulation Of Translation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Gene Silencing By RNA	Somite Specification Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Biological_process Positive Regulation Of Transcription By RNA Polymerase II Hematopoietic Stem Cell Differentiation Somite Development Sclerotome Development
Pathways		Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS		Carotid intima media thickness x smoking interaction ( 32117412)	Fractures ( 30158200)
Interacting Genes		4 interacting genes: C2CD6 FAM193B GPBP1L1 MEOX1	99 interacting genes: ACBD4 ACOT12 ALOX5 ANAPC2 APP APPL1 ATG9A BANP BNIP2 BYSL C14orf119 C1orf109 C1orf50 C2CD6 CACNB3 CCDC102B CCDC103 CDC34 CIAO1 CIB3 CKS1B CNOT11 CSNK2A1 CWF19L2 CYFIP1 DCX DUSP3 EIF4A3 EIF4EBP1 EMD FAM126B FMR1 GCC1 GEMIN2 GPANK1 GYS1 HMBOX1 HMGB3 HOMER3 HOXC8 INPP5J KANK2 KCTD7 L3MBTL2 LMNA MAPK9 MBD3 MCRS1 MEF2A MID1 MID2 MKRN3 MLX MORF4L1 MVP NAGK NDOR1 NEIL2 OSGIN1 PAGE3 PARVG PAX1 PAX3 PCP2 PDE4C PELI2 PIN1 PLCD4 PM20D2 POLR3GL PPM1F PRKAG1 PRKN QRICH1 RAD52 RANBP3 RBM41 RBM5 SDCBP SEC14L4 SOX10 SPAG8 SPIC SYT17 TCEANC TCP11L1 TEX33 TRAPPC2L TRIM41 TRIML2 TRIP10 TXLNA TXNL4B UBE2R2 UBXN2B UBXN7 UNC45A ZCCHC10 ZNF410
Entrez ID		55571	4222
HPRD ID		12812	02537
Ensembl ID		ENSG00000158435	ENSG00000005102
Uniprot IDs		Q9UKZ1	P50221
PDB IDs
Enriched GO Terms of Interacting Partners?
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