NPY4R and NPY

Data Source:
HPRD (in vitro)

		NPY4R	NPY
Description		neuropeptide Y receptor Y4	neuropeptide Y
Image
GO Annotations	Cellular Component		Extracellular Region Extracellular Space Golgi Apparatus Synapse Neuronal Dense Core Vesicle
	Molecular Function		G Protein-coupled Receptor Binding G Protein-coupled Receptor Activity Signaling Receptor Binding Hormone Activity Neuropeptide Hormone Activity Calcium Channel Regulator Activity Protein Binding Neuropeptide Y Receptor Binding
	Biological Process		G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Chemical Synaptic Transmission Feeding Behavior Regulation Of Blood Pressure Adult Feeding Behavior Central Nervous System Neuron Development Cerebral Cortex Development Neuron Projection Development Positive Regulation Of Appetite Intestinal Epithelial Cell Differentiation
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Peptide ligand-binding receptors G alpha (i) signalling events FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
Drugs		Peptide YY (3-36) Obinepitide TM30339	Phentermine 2-aminoisobutyric acid L-tyrosinamide
Diseases
GWAS			Adult body size ( 32376654) Aggressive periodontitis (sex interaction) ( 25256105) Body size at age 10 ( 32376654) Chronotype ( 30696823) Morning person ( 30696823) Periodontitis ( 23459936) Vitamin D levels ( 25208829)
Interacting Genes		3 interacting genes: NPY PPY PYY	16 interacting genes: ATP12A BAG6 GHRL MC4R MEP1A MEP1B NPFF NPFFR2 NPY1R NPY2R NPY4R NPY5R NR1H2 PMCH UBQLN1 UBQLN2
Entrez ID		5540	4852
HPRD ID		03476	01214
Ensembl ID		ENSG00000204174	ENSG00000122585
Uniprot IDs		P50391	A4D158 P01303
PDB IDs		2IK5	1QFA 1RON
Enriched GO Terms of Interacting Partners?
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