TBC1D2 and KCTD6

Data Source:
BioGRID (two hybrid)

		TBC1D2	KCTD6
Description		TBC1 domain family member 2	potassium channel tetramerization domain containing 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Cell Junction Cytoplasmic Vesicle	Cytosol M Band
	Molecular Function	GTPase Activator Activity Protein Binding Cadherin Binding	Protein Binding Ankyrin Binding Identical Protein Binding Cullin Family Protein Binding
	Biological Process	Intracellular Protein Transport Positive Regulation Of GTPase Activity Activation Of GTPase Activity Regulation Of Cilium Assembly	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Growth Post-translational Protein Modification Negative Regulation Of Smoothened Signaling Pathway Protein Homooligomerization
Pathways		TBC/RABGAPs	RUNX1 regulates estrogen receptor mediated transcription Neddylation Estrogen-dependent gene expression Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Post-traumatic stress disorder ( 26114229) Rate of ventricular enlargement ( 31711042) Severe influenza A (H1N1) infection ( 26379185)	Hepcidin/transferrin saturation ratio ( 27846281) Refractive error ( 32231278) Systemic lupus erythematosus ( 28714469) vWF levels ( 30586737)
Interacting Genes		9 interacting genes: AURKA BUB1 CCND1 DCC GABARAPL1 KCTD6 MAP1LC3A MLH3 PDGFRL	28 interacting genes: ACTN1 ACTN3 ANK1 BAG4 C8orf33 CDC23 CTNND1 CUL3 EHHADH ERBB2 FAM124B GOLGA8EP GOLGA8F GRB7 GSDMD LNX1 MOS NTAQ1 PICK1 PPIG PRPF31 PSMA1 REL SDCBP TBC1D2 TCEANC TEPSIN ZCCHC10
Entrez ID		55357	200845
HPRD ID		11624	13769
Ensembl ID		ENSG00000095383	ENSG00000168301
Uniprot IDs		A0A024R166 Q9BYX2	Q8NC69
PDB IDs		2DHK
Enriched GO Terms of Interacting Partners?
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