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TMEM19 and GJB1
Data Source:
BioGRID
(two hybrid)
TMEM19
GJB1
Description
transmembrane protein 19
gap junction protein beta 1
Image
No pdb structure
GO Annotations
Cellular Component
Membrane
Integral Component Of Membrane
Endoplasmic Reticulum Membrane
Connexin Complex
Integral Component Of Membrane
Molecular Function
Protein Binding
Gap Junction Channel Activity
Protein Binding
Biological Process
Cell-cell Signaling
Nervous System Development
Gap Junction Assembly
Transmembrane Transport
Pathways
Oligomerization of connexins into connexons
Oligomerization of connexins into connexons
Transport of connexins along the secretory pathway
Gap junction assembly
Drugs
Diseases
Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS
Nonsyndromic cleft lip with cleft palate (
28232668
)
Interacting Genes
38 interacting genes:
APOA5
AQP6
BSCL2
C10orf67
CD3G
CD79A
CNR2
CPLX4
CREB3
CREB3L1
ELOVL4
FAM210B
FCER1G
GJB1
GORAB
GPR42
GPRC5D
GPX8
HSD17B13
KASH5
LEPROTL1
LY6E
MC4R
MFSD14B
PGRMC2
PIGP
PTGES
REEP4
RNF185
SERTM1
SLC7A1
SUSD6
TEX29
TLCD4
TMEM139
TMEM14B
TMEM159
TMEM45A
57 interacting genes:
APOL3
APP
BMP10
C1GALT1
C2CD2L
C3orf52
CALM1
CD37
CD79A
CDIPT
CLEC7A
CMTM3
CMTM5
CNST
COMT
CTXN3
CXCL9
EFNA5
EGFR
EMP3
EPHA1
GJB2
GLP1R
GPR25
IER3IP1
ITGAM
LAT
LHFPL2
MAL
MAL2
MFF
MS4A13
MST1R
NDUFB11
NIPAL4
PRKACA
PRKCA
PTPN2
PTPN9
RTP2
SCD
SERTM1
SLC12A7
SRC
STX8
TEX264
TF
TM4SF4
TMEM120B
TMEM14C
TMEM19
TMEM218
TMEM98
UPK1B
VEGFA
VKORC1
YIPF6
Entrez ID
55266
2705
HPRD ID
15530
02367
Ensembl ID
ENSG00000139291
ENSG00000169562
Uniprot IDs
A0A024RBA1
Q96HH6
A0A654ICJ7
P08034
PDB IDs
1TXH
5KK9
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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