MOB1A and MST1

Data Source:
HPRD (in vivo)

		MOB1A	MST1
Description		MOB kinase activator 1A	macrophage stimulating 1
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytosol Extracellular Exosome	Extracellular Region Extracellular Space Collagen-containing Extracellular Matrix
	Molecular Function	Protein Binding Metal Ion Binding	Serine-type Endopeptidase Activity Protein Binding Receptor Tyrosine Kinase Binding
	Biological Process	Hippo Signaling	Proteolysis Regulation Of Macrophage Chemotaxis Positive Regulation Of Mammary Gland Epithelial Cell Proliferation Histone H2A-S139 Phosphorylation Negative Regulation Of Gluconeogenesis Hepatocyte Growth Factor Receptor Signaling Pathway Regulation Of CAMP-dependent Protein Kinase Activity
Pathways		Signaling by Hippo	Signaling by MST1
Drugs
Diseases
GWAS		Gestational age at birth (maternal effect) ( 28877031)	Blood protein levels ( 29875488 28240269) Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 18587394 28067908 17554261 17554300 21102463) Extremely high intelligence ( 29520040) Feeling miserable ( 29500382) Inflammatory bowel disease ( 28067908 23128233) Primary sclerosing cholangitis ( 23603763 27992413 21151127) Refractive error ( 32231278) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 19915572 28067908 20228799 25082827 21297633)
Interacting Genes		20 interacting genes: APP CCDC85B CMTM3 FAM118A FAM9B GMEB2 IKZF4 KANK2 KXD1 LZTFL1 MST1 PCYT1A PJA2 PTPN5 SEPTIN3 STRN3 TDO2 TMEM190 TRIM32 WASHC3	10 interacting genes: BECN1 FOXO1 KLKB1 MOB1A MST1R RASSF1 SERPINA3 TNNC1 TNNI3 TNNT2
Entrez ID		55233	4485
HPRD ID		14727	00798
Ensembl ID		ENSG00000114978	ENSG00000173531
Uniprot IDs		Q9H8S9	G3XAK1 P26927 Q53GN8
PDB IDs		1PI1 4J1V 4JIZ 5BRK 5BRM 5TWF 5TWG 5TWH 5XQZ 6MCP 6MCQ	2ASU 4QT8
Enriched GO Terms of Interacting Partners?
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