PPP2R2A and STRN3

Data Source:
HPRD (in vivo)

		PPP2R2A	STRN3
Description		protein phosphatase 2 regulatory subunit Balpha	striatin 3
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GO Annotations	Cellular Component	Protein Phosphatase Type 2A Complex Nucleoplasm Cytosol Glutamatergic Synapse	Nucleoplasm Golgi Apparatus Plasma Membrane Dendrite Protein-containing Complex Neuronal Cell Body FAR/SIN/STRIPAK Complex
	Molecular Function	Protein Binding Protein Phosphatase Regulator Activity Protein-containing Complex Binding Tau Protein Binding Protein Phosphatase 2A Binding	Protein Binding Calmodulin Binding Small GTPase Binding Protein-containing Complex Binding Protein Phosphatase 2A Binding Armadillo Repeat Domain Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Protein Dephosphorylation Mitotic Nuclear Envelope Reassembly Response To Morphine Regulation Of Phosphoprotein Phosphatase Activity Peptidyl-serine Dephosphorylation	Response To Estradiol Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Transcription, DNA-templated
Pathways		Initiation of Nuclear Envelope (NE) Reformation Cyclin D associated events in G1 Cyclin A/B1/B2 associated events during G2/M transition Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		2,6,8-Trimethyl-3-Amino-9-Benzyl-9-Methoxynonanoic Acid
Diseases
GWAS		Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Height ( 23563607) Schizophrenia ( 28991256) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)	Brain morphology (MOSTest) ( 32665545) Mean platelet volume ( 32888494) Platelet count ( 32888494)
Interacting Genes		13 interacting genes: BRAF CHEK2 CREBBP GRIN1 GRIN2D MTOR NDRG1 PPP2CA PPP2R1A PPP2R1B RRN3 STRN3 TGFBR1	10 interacting genes: CALM1 GABARAPL1 MOB1A NR3C1 PPP2R1A PPP2R1B PPP2R2A SIKE1 SLC2A4 TCEANC
Entrez ID		5520	29966
HPRD ID		09223	11613
Ensembl ID		ENSG00000221914	ENSG00000196792
Uniprot IDs		A0A140VJT0 A0A590UJJ1 P63151	Q13033
PDB IDs		3DW8	4N6J 6AKL 6IUR
Enriched GO Terms of Interacting Partners?
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