ARHGAP17 and TRIP10

Data Source:
BioGRID (two hybrid, two hybrid, pull down, affinity chromatography technology)
HPRD (in vitro, in vivo, two hybrid)

		ARHGAP17	TRIP10
Description		Rho GTPase activating protein 17	thyroid hormone receptor interactor 10
Image		No pdb structure
GO Annotations	Cellular Component	Intracellular Anatomical Structure Nucleoplasm Cytosol Plasma Membrane Bicellular Tight Junction	Phagocytic Cup Nucleoplasm Cytoplasm Lysosome Golgi Apparatus Cytosol Cytoskeleton Cell Cortex Cell Projection Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	GTPase Activator Activity Protein Binding SH3 Domain Binding	Protein Binding Lipid Binding Identical Protein Binding
	Biological Process	Actin Filament Organization Signal Transduction Calcium-ion Regulated Exocytosis Regulation Of Actin Cytoskeleton Organization Regulation Of Rac Protein Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Endocytosis Cell Communication Signal Transduction Actin Cytoskeleton Organization Regulation Of Small GTPase Mediated Signal Transduction Membrane Organization
Pathways		Rho GTPase cycle	Rho GTPase cycle Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)
Interacting Genes		16 interacting genes: ABL1 APP BTK CDC42 CRK CTTN DNMBP FNBP1 GRB2 LCK PACSIN1 PIK3R1 RAC1 SH3GLB1 SRC TRIP10	41 interacting genes: ABI1 ABL2 AKAP9 ARHGAP12 ARHGAP17 CDC42 CREBBP CTNNB1 DNM2 DTX3 HOXC11 HTT JRK LYN MEOX1 MEOX2 NKX2-5 PAX6 PDE6G POT1 PRKACA RHOJ RHOQ RIN1 RXRA SF3A2 SH3BP1 SMARCE1 SMURF1 SRC STAT3 TERF1 THAP1 THRB TINF2 UTF1 WAS WASF1 WASL WBP11 ZBTB7B
Entrez ID		55114	9322
HPRD ID		12207	05142
Ensembl ID		ENSG00000140750	ENSG00000125733
Uniprot IDs		Q68EM7	Q15642 W4VSQ9
PDB IDs			2CT4 2EFK 2KE4
Enriched GO Terms of Interacting Partners?
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