ATG2B and EVL

Data Source:
BioGRID (enzymatic study)

		ATG2B	EVL
Description		autophagy related 2B	Enah/Vasp-like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Phagophore Assembly Site Nucleoplasm Endoplasmic Reticulum Membrane Lipid Droplet Extrinsic Component Of Membrane Phagophore Assembly Site Membrane	Cytoplasm Cytosol Cytoskeleton Focal Adhesion Membrane Lamellipodium
	Molecular Function	Phosphatidylinositol-3-phosphate Binding Lipid Transfer Activity	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Piecemeal Microautophagy Of The Nucleus Late Nucleophagy Reticulophagy Intermembrane Lipid Transfer	Actin Filament Organization Cell Surface Receptor Signaling Pathway Nervous System Development Axon Guidance Actin Polymerization Or Depolymerization Animal Organ Morphogenesis Negative Regulation Of Epithelial Cell Migration Positive Regulation Of Actin Filament Polymerization Actin Nucleation Protein Homotetramerization Positive Regulation Of Stress Fiber Assembly Negative Regulation Of Ruffle Assembly
Pathways			Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors RHO GTPases Activate Formins
Drugs
Diseases
GWAS		Conotruncal heart defects (inherited effects) ( 28468790)	Blood protein levels ( 30072576) White matter hyperintensities ( 32358547) White matter hyperintensity burden ( 25663218)
Interacting Genes			33 interacting genes: ABI1 ABI3 ABL1 APBB1 APBB1IP CRKL DNMBP ENAH FYB1 FYN HCK HTT LYN PFN2 POT1 PRPF40A RAD51 SEMA6A SH3RF1 SPTA1 SPTAN1 SRC TCERG1 TERF1 TES TRIM9 VASP WAS WASL XIRP1 ZDHHC17 ZNF655 ZYX
Entrez ID		55102	51466
HPRD ID		12626	10942
Ensembl ID		ENSG00000066739	ENSG00000196405
Uniprot IDs		Q96BY7	A0A024R6K5 Q9UI08
PDB IDs
Enriched GO Terms of Interacting Partners?
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