DNAAF5 and OTUD4

Data Source:
BioGRID (affinity chromatography technology)

		DNAAF5	OTUD4
Description		dynein axonemal assembly factor 5	OTU deubiquitinase 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Motile Cilium	Nucleus Cytosol
	Molecular Function	Dynein Intermediate Chain Binding	RNA Binding Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Molecular Adaptor Activity Lys63-specific Deubiquitinase Activity
	Biological Process	Cilium Movement Outer Dynein Arm Assembly Inner Dynein Arm Assembly	Protein Deubiquitination Protein Phosphopantetheinylation Negative Regulation Of Toll-like Receptor Signaling Pathway Innate Immune Response Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Positive Regulation Of DNA Demethylation Regulation Of Protein K48-linked Deubiquitination Negative Regulation Of Interleukin-1-mediated Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Cerebrospinal P-tau181p levels ( 28247064) Initial pursuit acceleration ( 29064472)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Heel bone mineral density ( 30598549 28869591) Height ( 28552196) Hip circumference adjusted for BMI ( 25673412) Lung function (FEV1) ( 30061609) Malaria ( 31844061) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 31628463) Red blood cell count ( 32888494) Refractive error ( 32231278) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 27863252) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		2 interacting genes: FEZ1 ZBTB16	10 interacting genes: ALKBH3 EXOSC8 MAVS REL STAT1 TCF4 UBC USP7 VDR ZNF655
Entrez ID		54919	54726
HPRD ID		07903	11033
Ensembl ID		ENSG00000164818	ENSG00000164164
Uniprot IDs		B3KPE2 Q86Y56	Q01804
PDB IDs
Enriched GO Terms of Interacting Partners?
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