CMTM6 and CIAO2A

Data Source:
BioGRID (two hybrid)

		CMTM6	CIAO2A
Description		CKLF like MARVEL transmembrane domain containing 6	cytosolic iron-sulfur assembly component 2A
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane Early Endosome Membrane Azurophil Granule Membrane Specific Granule Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Membrane	Nucleoplasm Cytosol CIA Complex
	Molecular Function	Protein Binding	Protein Binding Metal Ion Binding
	Biological Process	Protein Transport Regulation Of Protein Stability Endocytic Recycling Neutrophil Degranulation	Chromosome Segregation Iron-sulfur Cluster Assembly Protein Maturation By Iron-sulfur Cluster Transfer Protein Maturation By [4Fe-4S] Cluster Transfer
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Beta blocker survival benefit in heart failure with reduced ejection fraction (time to all cause mortality x beta blocker interaction) ( 33012170) Cholesterol, total ( 24097068) LDL cholesterol ( 24097068 30275531) LDL cholesterol levels ( 32203549 28334899) Low density lipoprotein cholesterol levels ( 32154731) Total cholesterol levels ( 28334899 30275531)
Interacting Genes		23 interacting genes: APOA5 ATP13A2 BPIFA2 CD160 CD40 CIAO2A COQ8A DNMT3B DUSP10 ECPAS EHHADH FAM9B MIEF1 PPBP RBFA RBMX RUSC1 SNRPB2 SPG21 SUMO2 TCEA2 TMED8 XRCC6	25 interacting genes: AGTRAP APOA2 CIAO1 CMTM6 CREB3L1 DERL1 DGAT2L6 EBAG9 ERGIC3 FKBP7 GJA8 GSC2 KCNIP1 LIME1 MEST PLP2 PLPP6 PLPPR2 PRAF2 RHBDD2 SETD4 SIN3A TMED8 TNFRSF10D VAMP3
Entrez ID		54918	84191
HPRD ID		06987	08010
Ensembl ID		ENSG00000091317	ENSG00000166797
Uniprot IDs		Q9NX76	Q9H5X1
PDB IDs			2M5H 3UX2 3UX3
Enriched GO Terms of Interacting Partners?
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