YTHDF1 and LASP1

Data Source:
BioGRID (two hybrid)

		YTHDF1	LASP1
Description		YTH N6-methyladenosine RNA binding protein 1	LIM and SH3 protein 1
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GO Annotations	Cellular Component	Cytoplasm	Cytoplasm Focal Adhesion Cortical Actin Cytoskeleton
	Molecular Function	RNA Binding MRNA Binding Protein Binding Ribosome Binding N6-methyladenosine-containing RNA Binding	Protein Binding Ion Transmembrane Transporter Activity Cadherin Binding Metal Ion Binding Actin Filament Binding
	Biological Process	Immune System Process Regulation Of Antigen Processing And Presentation Learning Memory Positive Regulation Of Translation Positive Regulation Of Translational Initiation MRNA Destabilization Regulation Of Long-term Synaptic Potentiation Regulation Of Axon Guidance	Ion Transport Ion Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Response to cytadine analogues (cytosine arabinoside) ( 24483146)	Cognitive decline rate in late mild cognitive impairment ( 26252872) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912)
Interacting Genes		19 interacting genes: ABHD11 BATF2 C6orf15 FAM168A HEY1 HSF4 ITSN2 KRTAP13-1 KRTAP26-1 KRTAP7-1 KRTAP8-1 LASP1 MAGED1 MSX2 OIP5 PRR32 TLE5 VPS37C ZNF34	121 interacting genes: ACD ACTA1 ACTB ACTC1 ANKS1A ARHGEF15 ARHGEF16 ARID5A ATXN1 BAG4 BAHD1 BHLHE40 C14orf119 C19orf54 CAMK2A CATSPER1 CDK7 CERCAM CHERP COPS5 CRK CRYBA1 CRYBA2 CSTF2T CTNNA3 CYSRT1 DAZAP2 DMRT3 DNMT1 DOK6 DTX2 EHMT2 EVX2 FAM168A FAM168B FBXO17 FHL3 FOXH1 FXR2 GAS8 GCM2 GOLGA2 GUCD1 HGS HNRNPF HOXA1 INTS11 KRTAP10-8 KRTAP12-4 KRTAP19-3 KRTAP19-4 KRTAP19-6 KRTAP26-1 KRTAP3-2 KRTAP3-3 KRTAP4-2 KRTAP6-2 LENG8 LMO4 LZTS2 MDFI MED25 MGAT5B MKRN3 NOXA1 NUTF2 OTX1 OXER1 PITX1 PLSCR1 POLD1 POT1 POU1F1 PPP1R32 PRKAR2B PRKG1 PRKG2 PRR20A PRR20B PRR20C PRR20D PRR20E PRR35 PSMA3 QRICH1 RBFOX1 RBPMS RBPMS2 REL RHOXF2 RNF38 SEPTIN3 SPAG8 SPRY2 STAT3 TCF4 TEKT3 TEKT4 TEKT5 TERF1 TFG THAP1 TINF2 TLX3 TNS2 TRIM27 TRIP13 UBQLN2 UFSP1 UHRF1 VAC14 VEZF1 VGLL3 VPS37C WWOX YES1 YTHDF1 ZBTB9 ZC2HC1A ZC3H10 ZYX
Entrez ID		54915	3927
HPRD ID		11691	04229
Ensembl ID		ENSG00000149658	ENSG00000002834
Uniprot IDs		Q9BYJ9	A0A024R1S8 B4DIC4 Q14847
PDB IDs		4RCI 4RCJ	3I35
Enriched GO Terms of Interacting Partners?
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