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NDE1 and TSPOAP1
Data Source:
BioGRID
(two hybrid)
NDE1
TSPOAP1
Description
nudE neurodevelopment protein 1
TSPO associated protein 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Kinetochore
Condensed Chromosome Kinetochore
Centrosome
Cytosol
Kinesin Complex
Microtubule
Membrane
Spindle Pole Centrosome
Cleavage Furrow
Cytoplasm
Mitochondrion
Cytosol
Calyx Of Held
Glutamatergic Synapse
Molecular Function
Protein Binding
Microtubule Binding
Identical Protein Binding
Protein Binding
Benzodiazepine Receptor Binding
Voltage-gated Calcium Channel Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Levels
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Establishment Of Mitotic Spindle Orientation
Microtubule Nucleation
Chromosome Segregation
Mitotic Centrosome Separation
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Cell Migration
Cerebral Cortex Development
Cell Differentiation
Vesicle Transport Along Microtubule
Centrosome Duplication
Cell Division
Establishment Of Chromosome Localization
Centrosome Localization
Ciliary Basal Body-plasma Membrane Docking
Regulation Of Microtubule Motor Activity
C21-steroid Hormone Biosynthetic Process
Neurotransmitter Secretion
Neuromuscular Synaptic Transmission
Biological_process
Glutamate Secretion
Regulation Of Presynaptic Cytosolic Calcium Ion Concentration
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
RHO GTPases Activate Formins
Mitotic Prometaphase
AURKA Activation by TPX2
EML4 and NUDC in mitotic spindle formation
Serotonin Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Pregnenolone biosynthesis
Glutamate Neurotransmitter Release Cycle
Dopamine Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Drugs
Diseases
GWAS
Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) (
31374203
)
Mean platelet volume (
32888494
)
Multiple system atrophy (pathologically confirmed) (
27629089
)
Serum immune biomarker levels (
32066700
)
Serum uric acid levels in response to allopurinol in gout (
25676789
)
Interacting Genes
27 interacting genes:
AR
ARNT2
CDK1
DISC1
FAM9B
FBXO7
GOLGA2
HOXA2
LZTS2
MAPK1
MED4
MKRN3
NDC80
PAFAH1B1
REL
TFIP11
TRIM27
TSPOAP1
TTC1
TUBG1
UBQLN1
USHBP1
WAC
YWHAG
YWHAQ
ZNF365
ZNF398
19 interacting genes:
ANKRD11
ARNT2
BEND5
CACNA1A
CADPS2
CEP76
DISC1
DLGAP2
DLX2
GPRASP2
KHDRBS1
KIF1A
MVP
NDE1
RAPGEF4
REL
TCF4
TSC22D4
TSPO
Entrez ID
54820
9256
HPRD ID
14815
09832
Ensembl ID
ENSG00000072864
ENSG00000005379
Uniprot IDs
Q9NXR1
X5DP35
X5DR54
A7E2C5
B2RUT8
B7ZVZ7
O95153
X5DQQ3
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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