KLHL24 and ATP6V1C2

Data Source:
BioGRID (two hybrid)

		KLHL24	ATP6V1C2
Description		kelch like family member 24	ATPase H+ transporting V1 subunit C2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Adherens Junction Desmosome Axon Cul3-RING Ubiquitin Ligase Complex Perikaryon	Vacuolar Proton-transporting V-type ATPase, V1 Domain Lysosomal Membrane Cytosol Extracellular Exosome
	Molecular Function	Protein Binding	Identical Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Protein Ubiquitination Intermediate Filament Organization Protein Autoubiquitination Regulation Of Kainate Selective Glutamate Receptor Activity	Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Positive Regulation Of Wnt Signaling Pathway Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport
Pathways			ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS		Birth weight ( 31043758) Periventricular white matter hyperintensities ( 32517579) White matter hyperintensities ( 32358547)	Cardiac Troponin-T levels ( 23247143)
Interacting Genes		3 interacting genes: ATP6V1C2 KLHL12 NCK2	7 interacting genes: GOLGA2 KLHL24 KRTAP12-2 MEOX2 PAX6 REL SPANXN3
Entrez ID		54800	245973
HPRD ID		16838	16523
Ensembl ID		ENSG00000114796	ENSG00000143882
Uniprot IDs		Q6TFL4	A0A0U1RR16 Q8NEY4
PDB IDs
Enriched GO Terms of Interacting Partners?
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