ALKBH4 and MEPCE

Data Source:
BioGRID (genetic interference)

		ALKBH4	MEPCE
Description		alkB homolog 4, lysine demethylase	methylphosphate capping enzyme
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Midbody Contractile Ring	Nucleus 7SK SnRNP Ribonucleoprotein Complex
	Molecular Function	Actin Binding Protein Binding Oxidoreductase Activity 2-oxoglutarate-dependent Dioxygenase Activity Demethylase Activity Oxidative DNA Demethylase Activity Metal Ion Binding	RNA Binding Protein Binding O-methyltransferase Activity RNA Methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity SnRNA Binding 7SK SnRNA Binding RNA 5'-methyltransferase Activity
	Biological Process	Chromatin Organization Protein Demethylation Actomyosin Structure Organization Oxidative DNA Demethylation Cleavage Furrow Ingression Oxidative Demethylation DNA Demethylation Regulation Of Chromatin Organization	Negative Regulation Of Transcription By RNA Polymerase II RNA Methylation SnRNA Metabolic Process Negative Regulation Of Chromatin Binding SnRNA Modification Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of SnRNA Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Morning person ( 30696823)	Brain morphology (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		18 interacting genes: BPIFA1 DTX2 EIF3C EP300 FAM168A GORASP2 HSF4 LCN2 MLLT1 MLLT3 MTMR6 NIF3L1 PSMA6 TCF4 TES TRAF4 TXNL4B ZFHX3	2 interacting genes: ERBB2 RN7SK
Entrez ID		54784	56257
HPRD ID		07875	07889
Ensembl ID		ENSG00000160993	ENSG00000146834
Uniprot IDs		Q9NXW9	Q7L2J0
PDB IDs			5UNA 6DCB 6DCC
Enriched GO Terms of Interacting Partners?
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