PARP14 and PARP10

Data Source:
BioGRID (pull down)

		PARP14	PARP10
Description		poly(ADP-ribose) polymerase family member 14	poly(ADP-ribose) polymerase family member 10
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Membrane	Nucleus Nucleolus Cytoplasm Golgi Apparatus Cytosol
	Molecular Function	Transcription Corepressor Activity NAD+ ADP-ribosyltransferase Activity Protein Binding Enzyme Binding Protein ADP-ribosylase Activity	Transcription Corepressor Activity NAD+ ADP-ribosyltransferase Activity Protein Binding K63-linked Polyubiquitin Modification-dependent Protein Binding Protein ADP-ribosylase Activity
	Biological Process	Protein ADP-ribosylation Negative Regulation Of Gene Expression Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein Innate Immune Response Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Protein Poly-ADP-ribosylation Protein Mono-ADP-ribosylation Positive Regulation Of Interleukin-4-mediated Signaling Pathway	Protein ADP-ribosylation Negative Regulation Of Gene Expression Regulation Of Chromatin Assembly Translesion Synthesis Negative Regulation Of NF-kappaB Transcription Factor Activity NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway Negative Regulation Of Viral Genome Replication Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Fibroblast Proliferation Protein Poly-ADP-ribosylation Protein Auto-ADP-ribosylation Protein Mono-ADP-ribosylation Negative Regulation Of Protein K63-linked Ubiquitination
Pathways		Nicotinamide salvaging Maturation of nucleoprotein Maturation of nucleoprotein	Nicotinamide salvaging Maturation of nucleoprotein Maturation of nucleoprotein
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Brain morphology (MOSTest) ( 32665545) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Menarche (age at onset) ( 25231870) Red cell distribution width ( 32888494)
Interacting Genes		2 interacting genes: GPI PARP10	12 interacting genes: AURKA H2AC20 H2BC21 H3-3A H3C1 H4C1 MYC PARP14 PCNA PLK1 RAN UBC
Entrez ID		54625	84875
HPRD ID		11421	15100
Ensembl ID		ENSG00000173193	ENSG00000178685
Uniprot IDs		Q460N5 Q8N546	B4E0C4 E9PK67 E9PNI7 Q53GL7
PDB IDs		3GOY 3Q6Z 3Q71 3SE2 3SMI 3SMJ 3VFQ 4ABK 4ABL 4D86 4F1L 4F1Q 4PY4 5LXP 5LYH 5NQE 5O2D 5QHT 5QHU 5QHV 5QHW 5QHX 5QHY 5QHZ 5QI0 5QI1 5QI2 5QI3 5QI4 5QI5 5QI6 5QI7 5QI8 5QI9 5QIA 5V7T 5V7W 6FYM 6FZM 6G0W 7D2C	2DHX 3HKV 5LX6 6FXI
Enriched GO Terms of Interacting Partners?
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