POU3F3 and POU3F4

Data Source:
HPRD (in vitro)

		POU3F3	POU3F4
Description		POU class 3 homeobox 3	POU class 3 homeobox 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Chromatin Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Homodimerization Activity Sequence-specific DNA Binding HMG Box Domain Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Excretion Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Cerebral Cortex Radially Oriented Cell Migration Forebrain Ventricular Zone Progenitor Cell Division Negative Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Chemical Homeostasis Metanephric Ascending Thin Limb Development Metanephric Macula Densa Development Metanephric Thick Ascending Limb Development Metanephric Loop Of Henle Development Metanephric DCT Cell Differentiation	Regulation Of Transcription By RNA Polymerase II Brain Development Sensory Perception Of Sound Cochlea Morphogenesis Negative Regulation Of Mesenchymal Cell Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) General risk tolerance (MTAG) ( 30643258) Response to taxane treatment (docetaxel) ( 23006423) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Chronotype ( 30696823) Heschl's gyrus morphology ( 25130324)
Interacting Genes		5 interacting genes: POU3F4 PPP1R15A SOX10 SOX11 SOX8	4 interacting genes: HNRNPU POU3F1 POU3F2 POU3F3
Entrez ID		5455	5456
HPRD ID		03922	02076
Ensembl ID		ENSG00000198914	ENSG00000196767
Uniprot IDs		P20264	A0A2R8Y739 P49335
PDB IDs
Enriched GO Terms of Interacting Partners?
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