NDUFB11 and GJB1

Data Source:
BioGRID (two hybrid)

		NDUFB11	GJB1
Description		NADH:ubiquinone oxidoreductase subunit B11	gap junction protein beta 1
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Integral Component Of Membrane	Endoplasmic Reticulum Membrane Connexin Complex Integral Component Of Membrane
	Molecular Function	Protein Binding	Gap Junction Channel Activity Protein Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Mitochondrial Respiratory Chain Complex I Assembly	Cell-cell Signaling Nervous System Development Gap Junction Assembly Transmembrane Transport
Pathways		Respiratory electron transport Complex I biogenesis	Oligomerization of connexins into connexons Oligomerization of connexins into connexons Transport of connexins along the secretory pathway Gap junction assembly
Drugs
Diseases			Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS
Interacting Genes		11 interacting genes: BAG6 CLDN7 EBP FATE1 GJB1 GPR101 GPR152 GPR42 HIBADH PPBP TIMMDC1	57 interacting genes: APOL3 APP BMP10 C1GALT1 C2CD2L C3orf52 CALM1 CD37 CD79A CDIPT CLEC7A CMTM3 CMTM5 CNST COMT CTXN3 CXCL9 EFNA5 EGFR EMP3 EPHA1 GJB2 GLP1R GPR25 IER3IP1 ITGAM LAT LHFPL2 MAL MAL2 MFF MS4A13 MST1R NDUFB11 NIPAL4 PRKACA PRKCA PTPN2 PTPN9 RTP2 SCD SERTM1 SLC12A7 SRC STX8 TEX264 TF TM4SF4 TMEM120B TMEM14C TMEM19 TMEM218 TMEM98 UPK1B VEGFA VKORC1 YIPF6
Entrez ID		54539	2705
HPRD ID		02323	02367
Ensembl ID		ENSG00000147123	ENSG00000169562
Uniprot IDs		Q9NX14	A0A654ICJ7 P08034
PDB IDs		5XTC 5XTD 5XTH 5XTI	1TXH 5KK9
Enriched GO Terms of Interacting Partners?
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