POU3F1 and POU3F4

Data Source:
HPRD (in vitro)

		POU3F1	POU3F4
Description		POU class 3 homeobox 1	POU class 3 homeobox 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex	Chromatin Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Axon Ensheathment Positive Regulation Of Gene Expression Myelination In Peripheral Nervous System Keratinocyte Differentiation Forebrain Development Positive Regulation Of Transcription, DNA-templated	Regulation Of Transcription By RNA Polymerase II Brain Development Sensory Perception Of Sound Cochlea Morphogenesis Negative Regulation Of Mesenchymal Cell Apoptotic Process
Pathways		EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
GWAS		Rheumatoid arthritis ( 23143596 20453842) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Waist-to-hip circumference ratio (ever vs never smoking interaction) ( 23192594)	Chronotype ( 30696823) Heschl's gyrus morphology ( 25130324)
Interacting Genes		3 interacting genes: HMGA1 HMGB2 POU3F4	4 interacting genes: HNRNPU POU3F1 POU3F2 POU3F3
Entrez ID		5453	5456
HPRD ID		03921	02076
Ensembl ID		ENSG00000185668	ENSG00000196767
Uniprot IDs		Q03052	A0A2R8Y739 P49335
PDB IDs
Enriched GO Terms of Interacting Partners?
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