DHX29 and CENPT

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DHX29	CENPT
Description		DExH-box helicase 29	centromere protein T
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Intracellular Anatomical Structure Eukaryotic 43S Preinitiation Complex Cytosolic Small Ribosomal Subunit	Chromosome, Centromeric Region Kinetochore Condensed Nuclear Chromosome Kinetochore Nucleoplasm Cytosol Nuclear Body
	Molecular Function	RNA Binding RNA Helicase Activity Translation Initiation Factor Activity ATP Binding Translation Activator Activity Nucleoside-triphosphatase Activity Ribosomal Small Subunit Binding Cadherin Binding	DNA Binding Protein Binding Protein Heterodimerization Activity
	Biological Process	Formation Of Translation Preinitiation Complex Ribosome Assembly Positive Regulation Of Translational Initiation	Mitotic Cell Cycle Chromosome Segregation CENP-A Containing Nucleosome Assembly Chromosome Organization Cell Division Kinetochore Assembly Protein Localization To Kinetochore Involved In Kinetochore Assembly
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Cocaine dependence ( 31212010)	Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		3 interacting genes: CENPT PISD TBC1D17	8 interacting genes: APP CENPW COPS5 DHX29 H3C1 PPCDC SNCB TCEA2
Entrez ID		54505	80152
HPRD ID		10882	07811
Ensembl ID		ENSG00000067248	ENSG00000102901
Uniprot IDs		Q7Z478	B3KPB2 Q96BT3
PDB IDs
Enriched GO Terms of Interacting Partners?
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