OTULINL and HSD17B11

Data Source:
BioGRID (two hybrid)

		OTULINL	HSD17B11
Description		OTU deubiquitinase with linear linkage specificity like	hydroxysteroid 17-beta dehydrogenase 11
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GO Annotations	Cellular Component	Nuclear Envelope Cytoplasm Extrinsic Component Of Endoplasmic Reticulum Membrane	Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol
	Molecular Function	Protein Binding Ubiquitin-like Protein-specific Protease Activity Ubiquitin Binding	Estradiol 17-beta-dehydrogenase Activity Protein Binding Steroid Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
	Biological Process	Protein Deubiquitination	Estrogen Biosynthetic Process Androgen Catabolic Process
Pathways			Estrogen biosynthesis
Drugs			Aetiocholanolone
Diseases
GWAS		Asthma ( 32296059)	Appendicular lean mass ( 28724990) Bulimia nervosa ( 23568457) Lean body mass ( 28724990)
Interacting Genes		10 interacting genes: AQP6 GOLT1A HSD17B11 JAGN1 RETREG3 SLC30A8 TMEM14B TMEM31 TMEM86B TMX2	59 interacting genes: ADIPOQ AGPAT3 AGPAT4 ANKRD46 BNIP1 CMTM3 CSGALNACT2 CYBC1 DGAT2L6 DHRSX EHHADH ERG28 FAM241B GIMAP1 GOLT1A HTATIP2 LNPEP LRCH4 MS4A1 NEU1 ORMDL1 OTULINL PLP2 PRAF2 PTPN9 RASGRP3 RMDN2 RTP2 SEC22A SEC22B SERPINE1 SFRP4 SFT2D2 SFXN3 SLC22A18 SLC25A46 SLC30A8 STRIT1 STX5 STX7 SYS1 TMEM120B TMEM128 TMEM14B TMEM167B TMEM203 TMEM242 TMEM42 TMEM65 TMX2 TPRG1 TTPA TVP23B UBC UNC50 VAPA VEZT YIF1A YIPF6
Entrez ID		54491	51170
HPRD ID		07733	10881
Ensembl ID		ENSG00000145569	ENSG00000198189
Uniprot IDs		Q9NUU6	Q8NBQ5
PDB IDs		6DRM	1YB1
Enriched GO Terms of Interacting Partners?
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