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ANKIB1 and NR4A1
Data Source:
BioGRID
(pull down)
ANKIB1
NR4A1
Description
ankyrin repeat and IBR domain containing 1
nuclear receptor subfamily 4 group A member 1
Image
No pdb structure
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Cytoplasm
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Mitochondrion
Cytosol
Nuclear Membrane
Molecular Function
Protein Binding
Ubiquitin Conjugating Enzyme Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Nuclear Receptor Activity
Protein Binding
Zinc Ion Binding
Glucocorticoid Receptor Binding
Protein Heterodimerization Activity
Sequence-specific Double-stranded DNA Binding
Biological Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Endothelial Cell Proliferation
Cell Migration Involved In Sprouting Angiogenesis
Regulation Of Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Signal Transduction
Intracellular Receptor Signaling Pathway
Endothelial Cell Chemotaxis
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Cellular Response To Fibroblast Growth Factor Stimulus
Fat Cell Differentiation
Negative Regulation Of Cell Cycle
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Type B Pancreatic Cell Proliferation
Cellular Response To Corticotropin-releasing Hormone Stimulus
Pathways
AKT phosphorylates targets in the nucleus
Nuclear Receptor transcription pathway
Constitutive Signaling by AKT1 E17K in Cancer
Drugs
Diseases
GWAS
Ambidextrousness (
32989287
)
Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) (
30120083
)
Interacting Genes
4 interacting genes:
KPNA2
NR4A1
UBC
UBE2L3
87 interacting genes:
ABCA5
ABCB11
ABCC13
ABCC6
ABCG8
AKT1
ANKIB1
ARHGEF10L
ARHGEF5
ATM
ATXN1
BBS10
BCL2
BCL2A1
BCL2L10
CD2AP
CDKN2D
CHD1L
CHD3
CHEK2
CPT1A
CUTA
DIABLO
EP300
FAF1
FXYD3
GADD45GIP1
GK
GLOD4
GLUD1
HADHA
HES1
HIF1A
HNRNPA2B1
HSP90AB1
KAT2B
KRTAP10-1
KRTAP10-5
LONRF1
LSS
MAP3K1
MAPK1
MAPK8
MED1
MED31
NACAD
NCOA1
NCOA2
NCOA3
NCOR2
NDRG1
NFKB1
NR3C1
PGBD1
PML
POLA2
PPARG
PPBP
PPM1A
PRDX4
PRDX6
RBL1
ROBO2
RPL7
RPS6KA1
RPS6KA3
RPS6KA5
RPS6KA6
RTN4
RXRA
RXRG
SERPINA4
SERPING1
SMAD3
SOCS4
STAT3
SUGT1
TCF4
TP53
TRAF2
TRIM28
TUBB4A
VASP
VHL
YWHAZ
ZNF331
ZNF579
Entrez ID
54467
3164
HPRD ID
10645
00744
Ensembl ID
ENSG00000001629
ENSG00000123358
Uniprot IDs
Q9P2G1
A0A024R126
F5GXF0
P22736
Q6ZMM6
PDB IDs
2QW4
3V3E
3V3Q
4JGV
4KZI
4KZJ
4KZM
4RE8
4REE
4REF
4RZE
4RZF
4RZG
4WHF
4WHG
6KZ5
6LC1
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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