SNTG1 and DGKZ

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		SNTG1	DGKZ
Description		syntrophin gamma 1	diacylglycerol kinase zeta
Image		No pdb structure
GO Annotations	Cellular Component	Intracellular Anatomical Structure Nucleus Cytoplasm Cytoskeleton Dystrophin-associated Glycoprotein Complex Syntrophin Complex Ruffle Membrane	Nucleus Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Nuclear Speck Lamellipodium Glutamatergic Synapse
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding Protein C-terminus Binding	NAD+ Kinase Activity Diacylglycerol Kinase Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding
	Biological Process	Cell Communication	Phosphatidic Acid Biosynthetic Process Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Cell Migration Platelet Activation Intracellular Signal Transduction Diacylglycerol Metabolic Process Glycerolipid Metabolic Process Lipid Phosphorylation Negative Regulation Of T Cell Receptor Signaling Pathway Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of 1-phosphatidylinositol-4-phosphate 5-kinase Activity
Pathways			Effects of PIP2 hydrolysis
Drugs			alpha-Tocopherol succinate
Diseases
GWAS		Abstraction and mental flexibility ( 31596458) Diastolic blood pressure ( 27841878) General risk tolerance (MTAG) ( 30643258) Interleukin-6 levels ( 22205395) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681) Pulmonary function ( 17903307) Pulse pressure ( 27841878) Remission after SSRI treatment in MDD or openness ( 29559929) Response to SSRI in MDD or openness ( 29559929) Superior frontal gyrus grey matter volume ( 25335168) Systolic blood pressure ( 27841878 30578418)	Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Body size at age 10 ( 32376654) Immunoglobulin A ( 20694011) Reaction time ( 29844566) Schizophrenia ( 28991256 29483656)
Interacting Genes		15 interacting genes: ADRA1D DGKZ DMD DTNA DTNB FGF2 KCNA4 PLEKHA1 PLEKHA2 SNAP23 STXBP3 TGFBR1 UBC VPS45 VTN	19 interacting genes: DMD HRAS LEPR MAPK6 PLCG1 POLR2M PRKCA RASGRP1 RB1 RBL1 RBL2 SAT1 SNTA1 SNTB1 SNTB2 SNTG1 SNX27 SRC TP53
Entrez ID		54212	8525
HPRD ID		16373	03260
Ensembl ID		ENSG00000147481	ENSG00000149091
Uniprot IDs		A0A024R7Y0 A0A2R8Y5T2 A0A2R8Y631 B2RA84 Q9NSN8	Q13574
PDB IDs			5ELQ
Enriched GO Terms of Interacting Partners?
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