PRRX1 and QSOX1

Data Source:
BioGRID (two hybrid)

		PRRX1	QSOX1
Description		paired related homeobox 1	quiescin sulfhydryl oxidase 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol	Golgi Membrane Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Integral Component Of Golgi Membrane Platelet Alpha Granule Lumen Specific Granule Lumen Intracellular Membrane-bounded Organelle Intercellular Bridge Extracellular Exosome Tertiary Granule Lumen
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding HMG Box Domain Binding	Protein Disulfide Isomerase Activity Flavin-linked Sulfhydryl Oxidase Activity FAD Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Mesenchymal Cell Proliferation Regulation Of Transcription By RNA Polymerase II Embryonic Limb Morphogenesis Inner Ear Morphogenesis Middle Ear Morphogenesis Positive Regulation Of Smoothened Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Neuron Fate Determination Embryonic Cranial Skeleton Morphogenesis Artery Morphogenesis Cartilage Development Roof Of Mouth Development Regulation Of Neuron Projection Regeneration Neuronal Stem Cell Population Maintenance Positive Regulation Of DNA Repair By Transcription From RNA Polymerase II Promoter	Platelet Degranulation Protein Folding Negative Regulation Of Macroautophagy Protein Phosphopantetheinylation Neutrophil Degranulation Post-translational Protein Modification Cellular Protein Metabolic Process Extracellular Matrix Assembly
Pathways			Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Atrial fibrillation ( 28416818 28416822 29290336 29892015 22544366) Blood protein levels ( 29875488) Calcific aortic valve stenosis ( 32141789) Central corneal thickness ( 32528159) Early onset atrial fibrillation ( 28460022) Emphysema imaging phenotypes ( 26030696) Estimated glomerular filtration rate ( 31152163) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) Hip circumference adjusted for BMI ( 28552196 25673412) Intraocular pressure ( 29617998) Ischemic stroke (cardioembolic) ( 29531354) Macular thickness ( 30535121) Male-pattern baldness ( 29146897 28196072) PR interval ( 32439900) Prevalent atrial fibrillation ( 28416818) Refractive error ( 32231278) Response to angiotensin II receptor blocker therapy ( 22566498) Systemic lupus erythematosus ( 33536424) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Anorexia nervosa ( 23568457) Blood protein levels ( 29875488) Pulse pressure ( 30224653 30578418)
Interacting Genes		8 interacting genes: CINP GTF2I MAFF MAFG SAAL1 SOX10 SRF SUOX	6 interacting genes: BEGAIN CCR1 CCR6 CHRM4 UBE2D2 UBQLN4
Entrez ID		5396	5768
HPRD ID		01337	06785
Ensembl ID		ENSG00000116132	ENSG00000116260
Uniprot IDs		P54821	A0A140VKE5 O00391 Q13876
PDB IDs			3LLI 3LLK 3Q6O 4IJ3
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?