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PTOV1 and DMTN
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
PTOV1
DMTN
Description
PTOV1 extended AT-hook containing adaptor protein
dematin actin binding protein
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Transcription Regulator Complex
Plasma Membrane
Perinuclear Region Of Cytoplasm
Cytosol
Actin Filament
Plasma Membrane
Endomembrane System
Postsynaptic Density
Spectrin-associated Cytoskeleton
Actin Cytoskeleton
Cortical Cytoskeleton
Platelet Dense Tubular Network Membrane
Cell Projection Membrane
Cytoplasmic Vesicle
Perinuclear Region Of Cytoplasm
Molecular Function
Actin Binding
Signaling Receptor Binding
Protein Binding
Spectrin Binding
Protein Self-association
Actin Filament Binding
Biological Process
Positive Regulation Of Transcription By RNA Polymerase II
Cytoskeleton Organization
Regulation Of Cell Shape
Regulation Of Lamellipodium Assembly
Positive Regulation Of Fibroblast Migration
Negative Regulation Of Peptidyl-threonine Phosphorylation
Negative Regulation Of Cell-substrate Adhesion
Lamellipodium Assembly
Actin Cytoskeleton Organization
Positive Regulation Of Blood Coagulation
Regulation Of Actin Cytoskeleton Organization
Negative Regulation Of Peptidyl-serine Phosphorylation
Calcium-mediated Signaling Using Intracellular Calcium Source
Calcium-mediated Signaling Using Extracellular Calcium Source
Erythrocyte Development
Negative Regulation Of Peptidyl-tyrosine Phosphorylation
Actin Filament Bundle Assembly
Regulation Of Filopodium Assembly
Actin Filament Capping
Negative Regulation Of Focal Adhesion Assembly
Transmembrane Transport
Protein-containing Complex Assembly
Protein Secretion By Platelet
Cellular Response To Calcium Ion
Cellular Response To CAMP
Positive Regulation Of Wound Healing
Negative Regulation Of Protein Targeting To Membrane
Actin Filament Reorganization
Negative Regulation Of Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of Platelet Aggregation
Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways
Miscellaneous transport and binding events
Drugs
Diseases
GWAS
Apolipoprotein B levels (
32203549
)
LDL cholesterol (
30275531
)
LDL cholesterol levels (
32203549
)
Low density lipoprotein cholesterol levels (
32154731
)
Total cholesterol levels (
30275531
)
Interacting Genes
9 interacting genes:
CCR4
DMTN
HDAC6
PIN1
RACK1
SPTAN1
TMCC2
UBC
USP16
16 interacting genes:
ACTB
ACTC1
APP
CEP76
DYNC1LI2
EPB42
GOLGA2
NEDD4L
PRKACA
PROCR
PTOV1
SNCA
SNRPD2
SPTB
TEX11
TRAF2
Entrez ID
53635
2039
HPRD ID
17929
00506
Ensembl ID
ENSG00000104960
ENSG00000158856
Uniprot IDs
A0A0C4DGR2
Q86YD1
Q08495
PDB IDs
1QZP
1ZV6
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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