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PLS3 and CUL4B
Data Source:
HPRD
(in vitro, in vivo, two hybrid)
PLS3
CUL4B
Description
plastin 3
cullin 4B
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Actin Filament
Plasma Membrane
Actin Filament Bundle
Nucleoplasm
Cytosol
SCF Ubiquitin Ligase Complex
Cullin-RING Ubiquitin Ligase Complex
Cul4B-RING E3 Ubiquitin Ligase Complex
Extracellular Exosome
Cul4-RING E3 Ubiquitin Ligase Complex
Molecular Function
Calcium Ion Binding
Actin Filament Binding
Damaged DNA Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Ubiquitin Protein Ligase Binding
Biological Process
Actin Filament Bundle Assembly
Actin Filament Network Formation
Bone Development
G1/S Transition Of Mitotic Cell Cycle
Nucleotide-excision Repair, DNA Damage Recognition
Nucleotide-excision Repair, DNA Duplex Unwinding
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair, Preincision Complex Stabilization
Nucleotide-excision Repair, Preincision Complex Assembly
Nucleotide-excision Repair, DNA Incision, 3'-to Lesion
Nucleotide-excision Repair, DNA Incision, 5'-to Lesion
Cellular Response To DNA Damage Stimulus
Proteasomal Protein Catabolic Process
Protein Ubiquitination
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Nucleotide-excision Repair, DNA Incision
Histone H2A Monoubiquitination
Ribosome Biogenesis
DNA Damage Response, Detection Of DNA Damage
Post-translational Protein Modification
Global Genome Nucleotide-excision Repair
UV-damage Excision Repair
Pathways
Recognition of DNA damage by PCNA-containing replication complex
DNA Damage Recognition in GG-NER
Formation of Incision Complex in GG-NER
Dual Incision in GG-NER
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Neddylation
Drugs
Diseases
Syndromic X-linked mental retardation, including: Turner type (MRXST); Siderius type (MRXSSD) ; Cabezas type (MRXC); Raymond type (MRXSR); Type10 (MRXS10); Type14 (MRXS14); Mental retardation with isolated growth hormone deficiency (MRGH)
GWAS
Gestational age at birth (maternal effect) (
28877031
)
Mean platelet volume (
32888494
)
Platelet count (
32888494
)
Platelet distribution width (
32888494
)
Preterm birth (maternal effect) (
28877031
)
Interacting Genes
2 interacting genes:
APP
ATXN2
25 interacting genes:
AHR
APP
AR
CAND1
COMMD1
DCUN1D4
DDB1
DDB2
DNMT3B
ESR1
HUWE1
KPNA2
KPNA4
KPNB1
NEDD8
PRDX3
PTEN
RBX1
RNF7
SALL2
SIN3A
TBL3
UBC
UBE2D3
ZMAT4
Entrez ID
5358
8450
HPRD ID
02133
02251
Ensembl ID
ENSG00000102024
ENSG00000158290
Uniprot IDs
B4DPW9
P13797
K4DI93
Q13620
PDB IDs
1AOA
1WJO
2DO7
4A0C
4A0L
4A64
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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