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PKM and LINC01554
Data Source:
BioGRID
(unspecified method, affinity chromatography technology)
PKM
LINC01554
Description
pyruvate kinase M1/2
long intergenic non-protein coding RNA 1554
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Nucleus
Cytoplasm
Mitochondrion
Rough Endoplasmic Reticulum
Cytosol
Cilium
Vesicle
Secretory Granule Lumen
Collagen-containing Extracellular Matrix
Extracellular Exosome
Pyruvate Kinase Complex
Extracellular Vesicle
Ficolin-1-rich Granule Lumen
Molecular Function
Magnesium Ion Binding
RNA Binding
MRNA Binding
Pyruvate Kinase Activity
Protein Binding
ATP Binding
Kinase Activity
MHC Class II Protein Complex Binding
Potassium Ion Binding
Identical Protein Binding
ADP Binding
Cadherin Binding
Thyroid Hormone Binding
Biological Process
Response To Hypoxia
Liver Development
Glycolytic Process
ATP Biosynthetic Process
Response To Nutrient
Response To Gravity
Programmed Cell Death
Response To Muscle Inactivity
Animal Organ Regeneration
Cellular Response To Insulin Stimulus
Pyruvate Biosynthetic Process
Neutrophil Degranulation
Skeletal Muscle Tissue Regeneration
Canonical Glycolysis
Positive Regulation Of Sprouting Angiogenesis
Positive Regulation Of Cytoplasmic Translation
Pathways
Neutrophil degranulation
Drugs
Pyruvic acid
L-Phospholactate
2-Phosphoglycolic Acid
6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one
1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine
1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine
Copper
Artenimol
Diseases
GWAS
Interacting Genes
55 interacting genes:
ANXA7
APP
ARAF
AURKB
CCR4
CDC25A
CDK4
CDKN1A
CTNNB1
DLC1
DUX4
EGLN3
ENO3
EPM2A
EXOSC5
FGFR1
GRB7
HERC1
HIF1A
HULC
KPNA1
LINC01554
LMO7
LNX1
MAPK1
MDM2
MYL2
MYOC
NAGK
NDRG1
NXT2
OLFM2
PAX8
PIN1
POLE2
PRKN
PTEN
RAF1
RAP1B
RCC1
RELA
RPP14
SHBG
SMN1
SORBS2
SUMO1
SUMO2
TERF1
TINF2
TK1
TRIM35
TRIM55
TRIM63
UCHL5
YWHAQ
141 interacting genes:
AARS1
ACADVL
ACIN1
ACTB
ACTG1
ACTN1
ACTN3
ACTR3
ALDOA
ANXA2
ANXA5
ANXA6
APEX1
ARHGAP1
ASS1
ATAD3A
ATIC
ATP5F1A
BZW2
CANX
CCT2
CCT3
CCT4
CCT6A
CCT7
CKAP4
CS
CTPS1
DDX3X
DDX46
DHX9
DNAH2
DNAJA1
DST
DYNC1H1
EDARADD
EEF1G
EEF2
EIF3A
EIF3E
EIF4A2
EIF4B
ENO1
ENO3
EPRS1
ERO1A
G3BP1
G6PD
GANAB
GAPDH
GARS1
GDI2
GPI
GTF2I
HIVEP2
HMCN1
HNRNPF
HSP90AA1
HSP90B1
HSPA1L
HSPA5
HSPA8
HSPA9
HSPD1
HYOU1
IDH1
IPO4
IPO7
IPO9
ITPR2
KARS1
KPNA1
KPNB1
KRT18
KRT7
KRT8
KRT8P3
LRPPRC
MCM7
MSN
MYO18A
NAP1L1
NAP1L4
NCBP1
NCL
NPM1
OLA1
OXCT1
PABPC1
PCBP2
PDIA3
PDIA6
PFAS
PGD
PGK1
PGM1
PHGDH
PKM
PLOD2
PMPCA
POR
PPP2R1A
PSMC1
PSMD2
PSMD7
PTBP1
RDX
RPL6
RPSA
RTCB
RTN4
SARS1
SEPTIN7
SEPTIN9
SERPINH1
SFPQ
SQSTM1
TARS1
TGFBI
THOP1
TKT
TTF2
TUBA1A
TUBA8
TUBB
TUBB2A
TUBB3
TUBB4A
TUBB4B
TUBB6
TUFM
TXNRD1
TYMP
UBA1
VCL
VCP
VIM
VPS35
WARS1
XPO1
XRCC5
Entrez ID
5315
202299
HPRD ID
01529
16896
Ensembl ID
ENSG00000067225
ENSG00000236882
Uniprot IDs
A0A024R5Z9
B4DNK4
P14618
V9HWB8
PDB IDs
1T5A
1ZJH
3BJF
3BJT
3G2G
3GQY
3GR4
3H6O
3ME3
3SRD
3SRF
3SRH
3U2Z
4B2D
4FXF
4FXJ
4G1N
4JPG
4QG6
4QG8
4QG9
4QGC
4RPP
4WJ8
4YJ5
5X0I
5X1V
5X1W
6B6U
6GG3
6GG4
6GG5
6GG6
6JFB
6NU1
6NU5
6NUB
6TTF
6TTH
6TTI
6TTQ
6V74
6V75
6V76
6WP3
6WP4
6WP5
6WP6
Enriched GO Terms of Interacting Partners
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