PIP4K2A and ODAD2

Data Source:
BioGRID (affinity chromatography technology)

		PIP4K2A	ODAD2
Description		phosphatidylinositol-5-phosphate 4-kinase type 2 alpha	outer dynein arm docking complex subunit 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Lysosome Autophagosome Cytosol Plasma Membrane	Axoneme Ciliary Base
	Molecular Function	Protein Binding ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidylinositol-5-phosphate 4-kinase Activity Protein Homodimerization Activity	Protein Binding
	Biological Process	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Regulation Of Autophagy Regulation Of Phosphatidylinositol 3-kinase Signaling Megakaryocyte Development Negative Regulation Of Insulin Receptor Signaling Pathway Phosphatidylinositol Phosphorylation Autophagosome-lysosome Fusion Vesicle-mediated Cholesterol Transport Negative Regulation Of 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate Biosynthetic Process Positive Regulation Of Autophagosome Assembly	Cilium Movement Regulation Of Cilium Beat Frequency Determination Of Left/right Symmetry Heart Development Ventricular System Development Outer Dynein Arm Assembly
Pathways		Synthesis of PIPs at the plasma membrane PI5P Regulates TP53 Acetylation PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Synthesis of PIPs in the nucleus
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (B-cell precursor) ( 23996088) Acute lymphoblastic leukemia (childhood) ( 29348612) Acute lymphoblastic leukemia in childhood (B cell precursor) ( 29632299) B-cell acute lymphoblastic leukaemia ( 31767839) Height ( 31562340) Lymphocyte percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Positive urgency ( 30718321) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		6 interacting genes: BTK GSTK1 MEIS3 RAC1 RPS6KB1 TEC	1 interacting genes: NR4A2
Entrez ID		5305	55130
HPRD ID		11931	10663
Ensembl ID		ENSG00000150867	ENSG00000169126
Uniprot IDs		P48426	A0A140VKF7 A0A5F9ZH22 B7Z7A1 B7Z7Y0 Q5T2S8
PDB IDs		2YBX 6OSP
Enriched GO Terms of Interacting Partners?
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