PFKM and NDUFB2

Data Source:
BioGRID (two hybrid)

		PFKM	NDUFB2
Description		phosphofructokinase, muscle	NADH:ubiquinone oxidoreductase subunit B2
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GO Annotations	Cellular Component	Nucleus Cytosol 6-phosphofructokinase Complex Membrane Apical Plasma Membrane	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I
	Molecular Function	6-phosphofructokinase Activity Protein Binding ATP Binding Protein C-terminus Binding AMP Binding Kinase Binding Identical Protein Binding Metal Ion Binding Monosaccharide Binding Fructose Binding Fructose-6-phosphate Binding	NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Fructose 6-phosphate Metabolic Process Glycolytic Process Fructose 1,6-bisphosphate Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Muscle Cell Cellular Homeostasis Glycolytic Process Through Fructose-6-phosphate Canonical Glycolysis	Mitochondrial Electron Transport, NADH To Ubiquinone Mitochondrial Respiratory Chain Complex I Assembly
Pathways		Glycolysis	Respiratory electron transport Complex I biogenesis
Drugs			NADH
Diseases		Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS		Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) Immature fraction of reticulocytes ( 32888494) Longevity (90 years and older) ( 25199915) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Pulse pressure ( 30578418) Red blood cell count ( 32888494)
Interacting Genes		19 interacting genes: ATP6V0A4 CAV3 DLC1 DYNLL1 FHL2 HGS LSM7 MAPK3 NDUFB2 NOS1 PCNA PDGFRL PFKL SFRP2 SFRP4 SIAH1 SUMO2 TEAD4 UBTD1	6 interacting genes: AGR2 CDC7 LCN2 MEOX2 NDUFB7 PFKM
Entrez ID		5213	4708
HPRD ID		01988	11953
Ensembl ID		ENSG00000152556	ENSG00000090266
Uniprot IDs		A0A024R0Y5 A0A2R8Y891 P08237	A4D1T5 O95178
PDB IDs		4OMT	5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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