ACP1 and SFMBT1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ACP1	SFMBT1
Description		acid phosphatase 1	Scm like with four mbt domains 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoplasmic Side Of Plasma Membrane Extracellular Exosome	Nucleus Nucleoplasm
	Molecular Function	Acid Phosphatase Activity Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding	Chromatin Binding Transcription Corepressor Activity Protein Binding Histone Binding
	Biological Process	Peptidyl-tyrosine Dephosphorylation	Chromatin Organization Spermatogenesis Cell Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Muscle Organ Development
Pathways
Drugs		Adenine 4-Nitrophenyl Phosphate
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Large artery stroke ( 28265093) Night sleep phenotypes ( 27126917) Plateletcrit ( 32888494) Refractive error ( 32231278)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Chronic kidney disease ( 29124443) Creatinine levels ( 29124443) Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) ( 30120083) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31152163 29124443) General cognitive ability ( 29844566) Gout ( 31578528) Hand grip strength ( 29691431) Height ( 28552196 31562340 31217584) Hip circumference ( 28552196) Hyperuricemia ( 29124443) Intelligence (MTAG) ( 29326435) Mental health study participation (completed survey) ( 31263887) Multiple sclerosis ( 31604244) Schizophrenia ( 28991256 23974872) Serum uric acid levels ( 30993211 29124443 29403010) Type 2 diabetes (age of onset) ( 28060188) Urate levels ( 31985003 31578528 23263486)
Interacting Genes		16 interacting genes: BARD1 CTNNB1 EPHA2 EPHB1 EPHB2 ERBB2 FABP4 FNBP1L FYN INSR KDR LCK MRPL20 SFMBT1 SPTAN1 ZAP70	11 interacting genes: ACP1 CLNK FAM214B HOXB9 PHC1 PHC2 PSMA1 SCMH1 SPANXN2 SRPK1 ZCCHC10
Entrez ID		52	51460
HPRD ID		08881	09539
Ensembl ID		ENSG00000143727	ENSG00000163935
Uniprot IDs		A0A140VK37 P24666 Q59EH3	A0A024R338 Q9UHJ3
PDB IDs		1XWW 3N8I 4Z99 4Z9A 4Z9B 5JNR 5JNS 5JNT 5KQG 5KQL 5KQM 5KQP 5PNT 6Y2V 6Y2W
Enriched GO Terms of Interacting Partners?
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