PHAX and ITIH1

Data Source:
BioGRID (affinity chromatography technology)

		PHAX	ITIH1
Description		phosphorylated adaptor for RNA export	inter-alpha-trypsin inhibitor heavy chain 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Centrosome Cytosol Cajal Body Neuronal Cell Body	Extracellular Region Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	RNA Binding Protein Binding Toxic Substance Binding	Serine-type Endopeptidase Inhibitor Activity Calcium Ion Binding
	Biological Process	SnRNA Export From Nucleus Protein Transport SnRNA Transcription By RNA Polymerase II Nuclear Export	Negative Regulation Of Endopeptidase Activity Hyaluronan Metabolic Process
Pathways		snRNP Assembly RNA polymerase II transcribes snRNA genes
Drugs			Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Colorectal cancer ( 30529582)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972 19416921 31043756) Blood protein levels ( 29875488) Body mass index ( 25673413) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cortical surface area (MOSTest) ( 32665545) General cognitive ability ( 29844566) Glaucoma (primary open-angle) ( 25173105) Osteoarthritis (hip) ( 30374069) Pulse pressure ( 30578418) Schizophrenia ( 25056061 29483656 23974872) Schizophrenia, schizoaffective disorder or bipolar disorder ( 24166486) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes		16 interacting genes: ASPSCR1 CDC42 GADD45G GRB7 MKNK1 NSFL1C PDPK1 RAD23A RPS6KA1 STK3 TNFSF11 TULP3 UBXN2A VAV1 XPO1 ZWINT	2 interacting genes: PIK3CA SOX4
Entrez ID		51808	3697
HPRD ID		15122	00927
Ensembl ID		ENSG00000164902	ENSG00000055957
Uniprot IDs		Q9H814	B7Z8B6 P19827
PDB IDs		2XC7	6FPY 6FPZ
Enriched GO Terms of Interacting Partners?
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