MYOZ2 and ETF1

Data Source:
BioGRID (biochemical)

		MYOZ2	ETF1
Description		myozenin 2	eukaryotic translation termination factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Actin Cytoskeleton Sarcomere Z Disc	Nucleus Cytoplasm Cytosol Translation Release Factor Complex
	Molecular Function	Actin Binding Protein Binding Protein Phosphatase 2B Binding Telethonin Binding FATZ Binding	RNA Binding Translation Release Factor Activity Protein Binding Translation Termination Factor Activity Translation Release Factor Activity, Codon Specific Ribosome Binding Sequence-specific MRNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Tissue Development Biological_process Skeletal Muscle Fiber Adaptation Sarcomere Organization Negative Regulation Of Calcineurin-NFAT Signaling Cascade	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translational Termination Translational Termination Regulation Of Translational Termination Protein Methylation
Pathways			Eukaryotic Translation Termination Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Immature fraction of reticulocytes ( 32888494) PR interval ( 32439900) Refractive error ( 32231278)	Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 28552196) California verbal learning test score ( 31596458) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) General risk tolerance (MTAG) ( 30643258) Schizophrenia ( 28991256 25056061 29483656 30285260)
Interacting Genes		18 interacting genes: ACTN1 ACTN2 ACTN4 CRK DRICH1 EWSR1 FLNC HSPB2 LDB3 MBLAC1 MKRN3 MYB PDLIM3 PPP3CA PPP3CB RBPMS WWOX ZDHHC17	5 interacting genes: GSPT1 GSPT2 KEAP1 LIG4 PPP2CA
Entrez ID		51778	2107
HPRD ID		05724	02616
Ensembl ID		ENSG00000172399	ENSG00000120705
Uniprot IDs		Q9NPC6	B7Z7P8 P62495
PDB IDs			1DT9 2HST 2KTU 2KTV 2LGT 2LLX 2MQ6 2MQ9 3E1Y 3J5Y 3JAG 3JAH 3JAI 4D5N 4D61 5A8L 5LZT 5LZU 5LZV 6D90 6IP8 6XA1 6ZME
Enriched GO Terms of Interacting Partners?
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