SYT17 and SDCBP2

Data Source:
BioGRID (two hybrid)

		SYT17	SDCBP2
Description		synaptotagmin 17	syndecan binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Exocytic Vesicle	Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Nuclear Speck Extracellular Exosome
	Molecular Function	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Syntaxin Binding Clathrin Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Protein C-terminus Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Cell Differentiation Cellular Response To Calcium Ion Positive Regulation Of Dendrite Extension	Nervous System Development Cell Population Proliferation Intracellular Signal Transduction Intracellular Transport
Pathways
Drugs
Diseases
GWAS		Alcohol dependence ( 21876473) Fruit consumption ( 32066663) Parkinson's disease ( 27182965) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)	Estimated glomerular filtration rate ( 31152163) Metabolite levels ( 23823483)
Interacting Genes		50 interacting genes: AK8 APP APTX BLZF1 CBY2 CCDC102B CCDC33 CCDC85B CCNB1IP1 CEP63 CEP70 CHMP4A COG6 DEPDC5 EXOC8 FAM9B FRMD6 GMCL1 GOLGA2 GOLGA6A HIP1 HOOK2 IKZF1 LSM7 LZTS1 LZTS2 MAD1L1 MAJIN MCC MEOX1 MEOX2 MID2 NIF3L1 NINL PFDN5 PIBF1 PICK1 POF1B RUNDC3A SDCBP2 SNRNP35 SSX2IP TRAF2 TRIM27 TSC22D4 TSNAX VPS9D1 ZNF438 ZNF597 ZRANB1	65 interacting genes: ADAP1 AKAP17A AP1M1 ARF4 BEND7 C1orf35 CHCHD1 CRCT1 CRY2 CT45A1 CT45A10 CT45A3 CT45A5 CTH DMC1 DPPA2 EIF1AD FAM133A FAM13C FAM9B FBXO28 GABRA3 HSBP1 LGALS14 LGALS2 LYAR MED4 NFASC NFU1 NKAPD1 NOP56 NPM2 NRXN1 NUF2 PAFAH1B3 PHC1 PRM2 PRPF38A PRPF40A PRR13 PTMS RNF111 RNPS1 RPL22 RPL22L1 RPL41 SDCBP SEC23A SREK1IP1 SYT17 TCP11L1 TDO2 THAP6 TIFA TM4SF1 TNNT1 TNP1 TRAF1 VAX1 VPS25 YTHDC1 ZCCHC10 ZCCHC17 ZNF581 ZRSR2
Entrez ID		51760	27111
HPRD ID		17425	18032
Ensembl ID		ENSG00000103528	ENSG00000125775
Uniprot IDs		H3BN78 H3BRH9 Q9BSW7	Q9H190
PDB IDs		2ENP
Enriched GO Terms of Interacting Partners?
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