PDE6B and THTPA

Data Source:
BioGRID (biochemical)

		PDE6B	THTPA
Description		phosphodiesterase 6B	thiamine triphosphatase
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Photoreceptor Outer Segment Membrane Photoreceptor Disc Membrane	Cytosol
	Molecular Function	3',5'-cyclic-nucleotide Phosphodiesterase Activity Metal Ion Binding 3',5'-cyclic-GMP Phosphodiesterase Activity	Magnesium Ion Binding Protein Binding Hydrolase Activity Thiamin-triphosphatase Activity
	Biological Process	Signal Transduction Wnt Signaling Pathway, Calcium Modulating Pathway Visual Perception Phototransduction, Visible Light Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Entrainment Of Circadian Clock By Photoperiod Retina Development In Camera-type Eye	Generation Of Precursor Metabolites And Energy Thiamine Metabolic Process Dephosphorylation Thiamine Diphosphate Metabolic Process Thiamine-containing Compound Metabolic Process
Pathways		Activation of the phototransduction cascade Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Ca2+ pathway Ca2+ pathway	Vitamin B1 (thiamin) metabolism
Drugs		Caffeine Trapidil
Diseases		Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO) Retinitis pigmentosa (RP)
GWAS
Interacting Genes			1 interacting genes: TLX3
Entrez ID		5158	79178
HPRD ID		01571	15505
Ensembl ID		ENSG00000133256	ENSG00000259431
Uniprot IDs		B4DHV7 P35913	G3V5Q5 Q9BU02
PDB IDs			3BHD 3TVL
Enriched GO Terms of Interacting Partners?
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