PDE6B

Description		phosphodiesterase 6B
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Photoreceptor Outer Segment Membrane Photoreceptor Disc Membrane
	Molecular Function	3',5'-cyclic-nucleotide Phosphodiesterase Activity Metal Ion Binding 3',5'-cyclic-GMP Phosphodiesterase Activity
	Biological Process	Signal Transduction Wnt Signaling Pathway, Calcium Modulating Pathway Visual Perception Phototransduction, Visible Light Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Entrainment Of Circadian Clock By Photoperiod Retina Development In Camera-type Eye
Pathways		Activation of the phototransduction cascade Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Ca2+ pathway Ca2+ pathway
Drugs		Caffeine Trapidil
Diseases		Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO) Retinitis pigmentosa (RP)
GWAS
Novel Interacting Genes		2 novel interacting genes: GLA THTPA
Interacting Genes
Entrez ID		5158
HPRD ID		01571
Ensembl ID		ENSG00000133256
Uniprot IDs		B4DHV7 P35913
PDB IDs
Enriched GO Terms of Interacting Partners?
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