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ACKR4 and CCL11
Data Source:
HPRD
(in vitro)
ACKR4
CCL11
Description
atypical chemokine receptor 4
C-C motif chemokine ligand 11
Image
No pdb structure
GO Annotations
Cellular Component
Early Endosome
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Recycling Endosome
Extracellular Region
Extracellular Space
Molecular Function
Chemokine Receptor Activity
Scavenger Receptor Activity
Protein Binding
C-C Chemokine Receptor Activity
C-C Chemokine Binding
Protein Binding
Chemokine Activity
CCR3 Chemokine Receptor Binding
Protein Dimerization Activity
Receptor Ligand Activity
CCR Chemokine Receptor Binding
Biological Process
Endocytosis
Chemotaxis
Immune Response
G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Calcium-mediated Signaling
Cell Chemotaxis
Chemokine-mediated Signaling Pathway
Positive Regulation Of Endothelial Cell Proliferation
Chronic Inflammatory Response
Monocyte Chemotaxis
Mast Cell Chemotaxis
Protein Phosphorylation
Cellular Calcium Ion Homeostasis
Chemotaxis
Inflammatory Response
Cytoskeleton Organization
Actin Filament Organization
Cell Adhesion
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Learning Or Memory
Regulation Of Cell Shape
Response To Radiation
Response To Virus
Cytokine-mediated Signaling Pathway
Positive Regulation Of Cell Migration
Neutrophil Chemotaxis
Positive Regulation Of Actin Filament Polymerization
Response To Interleukin-13
Positive Regulation Of GTPase Activity
Positive Regulation Of Angiogenesis
Eosinophil Chemotaxis
Lymphocyte Chemotaxis
Negative Regulation Of Neurogenesis
Branching Involved In Mammary Gland Duct Morphogenesis
Mammary Duct Terminal End Bud Growth
Chemokine-mediated Signaling Pathway
ERK1 And ERK2 Cascade
Positive Regulation Of ERK1 And ERK2 Cascade
Response To Interleukin-4
Cellular Response To Interferon-gamma
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Modulation Of Age-related Behavioral Decline
Pathways
Chemokine receptors bind chemokines
Chemokine receptors bind chemokines
Interleukin-4 and Interleukin-13 signaling
Drugs
CAT-213
Diseases
GWAS
Blood protein levels (
28240269
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Neonatal cytokine/chemokine levels (fetal genetic effect) (
30134952
)
Subcortical volume (MOSTest) (
32665545
)
Crohn's disease (
28067908
22412388
)
Gut microbiota (functional units) (
27694959
)
Inflammatory bowel disease (
28067908
23128233
)
Interacting Genes
11 interacting genes:
CCL11
CCL13
CCL19
CCL2
CCL21
CCL25
CCL5
CCL7
CCL8
CDK2
CXCL13
29 interacting genes:
ACKR2
ACKR4
CCL13
CCL14
CCL18
CCL2
CCL26
CCL27
CCL28
CCL5
CCL8
CCR3
CCR5
CXCL1
CXCL10
CXCL11
CXCL12
CXCL14
CXCL2
CXCL3
CXCL5
CXCL6
CXCL9
DPP4
NUDT3
PF4
PF4V1
TPI1
XCL1
Entrez ID
51554
6356
HPRD ID
07298
03098
Ensembl ID
ENSG00000129048
ENSG00000172156
Uniprot IDs
Q9NPB9
P51671
Q6I9T4
PDB IDs
1EOT
2EOT
2MPM
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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